Area of research
Immunology and Allergy · Cell Biology
Research interest
Research interests include Cell Adhesion Molecules Research, Cellular Mechanics and Interactions, RNA Research and Splicing, and Cellular transport and secretion.
A CD25–chemokine receptor complex initiates noncanonical IL-2 signaling
AI is a viable alternative to high throughput screening: a 318-target study
AI is a viable alternative to high throughput screening: a 318-target study.
IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4<sup>+</sup> T Cells.
Phostensin enables lymphocyte integrin activation and population of peripheral lymphoid organs.
Kindlin-3 recruitment to the plasma membrane precedes high-affinity β2-integrin and neutrophil arrest from rolling.
Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells.
Talin-1 is the principal platelet Rap1 effector of integrin activation
Talin-1 is the principal platelet Rap1 effector of integrin activation
Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem.
Pharmacological inhibition of the heart of glass (HEG1)-Krev interaction trapped protein 1 (KRIT1) protein complex increases Krüppel-like Factors 4 and 2 (KLF4/2) expression in endothelial cells
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin
RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover
Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation
Integrins protect cardiomyocytes from ischemia/reperfusion injury
Talin Contains A C-Terminal Calpain2 Cleavage Site Important In Focal Adhesion Dynamics
Structural basis of the junctional anchorage of the cerebral cavernous malformations complex