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Claude Jourdan Le Saux

University of California, San Francisco · US
Area of research
Pulmonary and Respiratory Medicine · Physiology
Research interest
Research interests include Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, Telomeres, Telomerase, and Senescence, Caveolin-1 and cellular processes, and Neonatal Respiratory Health Research.
h-index
25
citations
2,953
works
75
NIH funding
primary concept
email

Recent publications

Peeling Back the Layers of the Bleomycin Model of Lung Fibrosis: Lessons Learned, Factors to Consider, and Future Directions
Seminars in Respiratory and Critical Care Medicine 2025cited by 5position: lastdoi
A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis
Journal of Clinical Investigation 2024cited by 66position: lastdoi
Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies
GeroScience 2023cited by 62position: middledoi
Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells
Nature Cell Biology 2021cited by 259position: middledoi
Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans
Science Translational Medicine 2020cited by 174position: middledoi
Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis
New England Journal of Medicine 2020cited by 87position: middledoi
Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis
JCI Insight 2019cited by 125position: lastdoi
Fibroblast-specific inhibition of TGF-β1 signaling attenuates lung and tumor fibrosis
Journal of Clinical Investigation 2017cited by 184position: middledoi
SMAD-Independent Down-Regulation of Caveolin-1 by TGF-β: Effects on Proliferation and Survival of Myofibroblasts
PLoS ONE 2015cited by 48position: middledoi
Streptococcus pneumoniae Translocates into the Myocardium and Forms Unique Microlesions That Disrupt Cardiac Function
PLoS Pathogens 2014cited by 195position: middledoi
Caveolin-1 Deficiency Protects from Pulmonary Fibrosis by Modulating Epithelial Cell Senescence in Mice
American Journal of Respiratory Cell and Molecular Biology 2012cited by 93position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Harold A. Chapman · Pulmonary and Allergy Associates5 papers (2017–2024)Ying Wei · Fanjingshan National Nature Reserve3 papers (2017–2020)Paul J. Wolters · Netherlands Organisation for Applied Scientific Research3 papers (2020–2024)Michael A. Matthay · Drexel University2 papers (2021–2024)Genevieve Montas · University of California, San Francisco2 papers (2020–2024)Kirk D. Jones · Florida College2 papers (2020–2024)Max Cohen · University of California, San Francisco2 papers (2021–2024)Darren Leong · East Kent Hospitals University NHS Foundation Trust2 papers (2020–2024)Victor J. Thannickal · University of Alabama at Birmingham2 papers (2012–2015)Julia Jackson · University of Minnesota2 papers (2017–2019) · 2 papers (2017–2019)Alexis N. Brumwell · Pulmonary and Allergy Associates2 papers (2019–2024)Binh N. Trinh · University of California, San Francisco2 papers (2020–2024)Jeffrey A. Golden · University of California, San Francisco2 papers (2020–2024)Ganesh V. Halade · University of Alabama at Birmingham1 papers (2014–2014)James I. Andorko · University of Maryland, College Park1 papers (2020–2020)Carlos J. Orihuela · University of Alabama at Birmingham1 papers (2014–2014) · 1 papers (2014–2014)Ashish Kurundkar · University of Alabama at Birmingham1 papers (2015–2015)Prerna Kotak · Pliant (United States)1 papers (2020–2020)