Area of research
Molecular Biology · Genetics
Research interest
Research interests include Protein Degradation and Inhibitors, Glioma Diagnosis and Treatment, Microtubule and mitosis dynamics, and Epigenetics and DNA Methylation.
Triptolide and its prodrug Minnelide target high-risk MYC-amplified medulloblastoma in preclinical models
RAPID resistance to BET inhibitors is mediated by FGFR1 in glioblastoma
Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping
Systematic Review of Epigenetic Therapies for Treatment of IDH-mutant Glioma
A dual aurora and lim kinase inhibitor reduces glioblastoma proliferation and invasion
A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth
Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer
Organoid Models of Glioblastoma and Their Role in Drug Discovery
The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling
The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion
Neuroinflammation Treatment via Targeted Delivery of Nanoparticles
Epigenetic pathways and plasticity in brain tumors
Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner
Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis
Serum long noncoding RNA HOTAIR as a novel diagnostic and prognostic biomarker in glioblastoma multiforme
Drug Repositioning in Glioblastoma: A Pathway Perspective
Drug and disease signature integration identifies synergistic combinations in glioblastoma
Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury
A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma
Immunotherapy and Epigenetic Pathway Modulation in Glioblastoma Multiforme
Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations
Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma
The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation
Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4
Casein Kinase 1δ Is an APC/CCdh1 Substrate that Regulates Cerebellar Granule Cell Neurogenesis
BET bromodomain proteins are required for glioblastoma cell proliferation
The BET Bromodomain Inhibitor I-BET151 Acts Downstream of Smoothened Protein to Abrogate the Growth of Hedgehog Protein-driven Cancers
Epigenetic Pathways and Glioblastoma Treatment: Insights From Signaling Cascades
Casein Kinase 1δ-dependent Wee1 Protein Degradation
Identifying Glioblastoma Gene Networks Based on Hypergeometric Test Analysis