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Bin Li

Anhui Provincial Hospital · US
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Area of research
Molecular Biology
Research interest
Research interests include Hedgehog Signaling Pathway Studies, Cancer-related gene regulation, Epigenetics and DNA Methylation, and Ubiquitin and proteasome pathways.
h-index
32
citations
2,971
works
149
NIH funding
primary concept
email

Recent publications

The role of interleukin-17 in inflammation-related cancers
Frontiers in Immunology 2025cited by 46position: middledoi
The Role of Troponin in the Diagnosis and Treatment of Acute Pulmonary Embolism: Mechanisms of Elevation, Prognostic Evaluation, and Clinical Decision-Making
Cureus 2024cited by 6position: middledoi
The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon
Journal of Biological Chemistry 2022cited by 8position: middledoi
Significance of Anoctamin 6 in progression and prognostic prediction of gastric adenocarcinoma.
PubMed 2022cited by 4position: firstdoi
The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling
Nature Communications 2021cited by 42position: middledoi
iTRAQ-based proteome analysis of porcine group A rotavirus-infected porcine IPEC-J2 intestinal epithelial cells
Journal of Proteomics 2021cited by 17position: lastdoi
The CK1α Activator Pyrvinium Enhances the Catalytic Efficiency (<i>k</i><sub>cat</sub>/<i>K</i><sub>m</sub>) of CK1α
Biochemistry 2019cited by 17position: middledoi
APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway
Developmental Cell 2018cited by 105position: middledoi
A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma
Clinical Cancer Research 2018cited by 30position: middledoi
Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors
Science Signaling 2017cited by 46position: firstdoi
Notch Represses Transcription by PRC2 Recruitment to the Ternary Complex
Molecular Cancer Research 2017cited by 39position: middledoi
Acetylation of Mastermind-like 1 by p300 Drives the Recruitment of NACK to Initiate Notch-Dependent Transcription
Cancer Research 2017cited by 37position: middledoi
Inhibition of the NEDD8 conjugation pathway induces calcium-dependent compensatory activation of the pro-survival MEK/ERK pathway in acute lymphoblastic leukemia
Oncotarget 2017cited by 18position: middledoi
Casein Kinase 1δ Is an APC/CCdh1 Substrate that Regulates Cerebellar Granule Cell Neurogenesis
Cell Reports 2015cited by 36position: middledoi
The BET Bromodomain Inhibitor I-BET151 Acts Downstream of Smoothened Protein to Abrogate the Growth of Hedgehog Protein-driven Cancers
Journal of Biological Chemistry 2014cited by 110position: middledoi
Notch Signaling Drives Stemness and Tumorigenicity of Esophageal Adenocarcinoma
Cancer Research 2014cited by 90position: middledoi
Pyrvinium Attenuates Hedgehog Signaling Downstream of Smoothened
Cancer Research 2014cited by 75position: firstdoi
Repurposing the FDA-Approved Pinworm Drug Pyrvinium as a Novel Chemotherapeutic Agent for Intestinal Polyposis
PLoS ONE 2014cited by 64position: firstdoi

Grants

Lattice Correspondence Analyses of Grain Boundary Formation and Migration in Hexagonal Close-Packed Metals
NSF2528624$442,2982026–2029PIRePORTER
Collaborative Research: CPS: Medium: Real-Time Crowd-Sourced Geospatial Digital Twin for Cyber-Physical Systems
NSF2331105$300,0002024–2027PIRePORTER
EAGER: TaskDCL: Collaborative Research: IMPACT: Interactive Mixed-Reality-Based Platform for AI-Driven Adaptive and Collaborative Task Training Environments
NSF2420351$150,0002024–2026PIRePORTER
CAREER: Wireless Collaborative Mixed Reality Networking: Foundations and Algorithms for Joint Communication, Computation, and Learning
NSF2152658$486,7532021–2026PIRePORTER
Collaborative Research: CNS Core: Medium: Foundations and Scalable Algorithms for Personalized and Collaborative Virtual Reality Over Wireless Networks
NSF2152610$218,0002021–2025PIRePORTER
NeTS: Small: Collaborative Research: Towards Adaptive and Efficient Wireless Computing Networks
NSF2152657$154,9952021–2023PIRePORTER
Collaborative Research: CNS Core: Medium: Foundations and Scalable Algorithms for Personalized and Collaborative Virtual Reality Over Wireless Networks
NSF2107080$50,5002021–2022PIRePORTER
CAREER: Wireless Collaborative Mixed Reality Networking: Foundations and Algorithms for Joint Communication, Computation, and Learning
NSF1942383$190,6202020–2021PIRePORTER
NeTS: Small: Collaborative Research: Towards Adaptive and Efficient Wireless Computing Networks
NSF1815563$250,0002018–2021PIRePORTER
NeTS: Small: Principles and Protocols for Traffic-Insensitive Performance in Wireless Networks
NSF1717108$317,3672017–2021PIRePORTER
Design of Twinning Induced Plasticity (TWIP) Magnesium Alloys
NSF1635088$468,5442016–2020PIRePORTER
CDS&E/Collaborative Research: Fundamental Investigation of Zinc-Coating of Advanced High Strength Steels Directed by Multiscale Modeling and Experiments
NSF1506944$307,6222015–2019PIRePORTER

Frequent collaborators

David J. Robbins · Georgetown University13 papers (2014–2022)Anthony J. Capobianco · General Motors (Poland)10 papers (2014–2021)Ethan Lee · Johns Hopkins University7 papers (2014–2022)Ke Jin · Sichuan University4 papers (2014–2017)Jun Long · Zhujiang Hospital4 papers (2014–2018)Chen Shen · Qingdao University4 papers (2017–2022)Dennis Liang Fei · National Cancer Institute4 papers (2014–2017)Feng Bai · Shanxi Medical University4 papers (2014–2014)Nagi G. Ayad · Georgetown University4 papers (2014–2021)Jezabel Rodríguez‐Blanco · Medical University of South Carolina4 papers (2014–2018)Darren Orton · Io Therapeutics (United States)4 papers (2014–2018)Xin‐Hai Pei · Chinese Academy of Medical Sciences & Peking Union Medical College4 papers (2014–2014)Fan Yang · Hebei Medical University3 papers (2018–2022)Xiaoqing Han · Ministry of Education of the People's Republic of China3 papers (2014–2017)Luisana Astudillo · University of Miami3 papers (2017–2019)Leif R. Neitzel · Michigan State University3 papers (2017–2022)Yashi Ahmed · Dartmouth College3 papers (2018–2022)Wen Zhou · Nanchang University2 papers (2017–2017)Prathibha Ranganathan · Manipal Academy of Higher Education2 papers (2014–2017)Charles H. Williams · Boston Medical Center2 papers (2021–2022)
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