Area of research
Molecular Biology · Pathology and Forensic Medicine
Research interest
Research interests include Genetic factors in colorectal cancer, Epigenetics and DNA Methylation, Cancer Genomics and Diagnostics, and RNA modifications and cancer.
Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers
The sensitivity of pan-TRK immunohistochemistry in solid tumours: A meta-analysis.
Accuracy of mutational signature software on correlated signatures.
mSigHdp: hierarchical Dirichlet process mixture modeling for mutational signature discovery
The mutational landscape of early- and typical-onset oral tongue squamous cell carcinoma.
Mutational processes in cancer preferentially affect binding of particular transcription factors.
The repertoire of mutational signatures in human cancer
The repertoire of mutational signatures in human cancer.
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
The mutational landscape of early‐ and typical‐onset oral tongue squamous cell carcinoma
Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types.
Recurrent APC Splice Variant c.835-8A>G in Patients With Unexplained Colorectal Polyposis Fulfilling the Colibactin Mutational Signature
A tumor-associated splice-isoform of <i>MAP2K7</i> drives dedifferentiation in MBNL1-low cancers via JNK activation.
Recurrent APC Splice Variant c.835-8A>G in Patients With Unexplained Colorectal Polyposis Fulfilling the Colibactin Mutational Signature.
Monoallelic NTHL1 Loss-of-Function Variants and Risk of Polyposis and Colorectal Cancer.
Multiple neoplasia in a patient with Gitelman syndrome harboring germline monoallelic <i>MUTYH</i> mutation.
Recurrent mutations in topoisomerase 2a cause a novel mutator phenotype in human cancers
Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes
Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes.
Allelic Switching of <i>DLX5</i>, <i>GRB10</i>, and <i>SVOPL</i> during Colorectal Cancer Tumorigenesis.
Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer