Area of research
Cancer Research · Pathology and Forensic Medicine
Research interest
Research interests include Cancer Genomics and Diagnostics, Genetic factors in colorectal cancer, Gastrointestinal Tumor Research and Treatment, and Financial Markets and Investment Strategies.
Novel CRISPR-Cas9 BAP1 knockout pre-clinical tumor model recapitulates human melanoma tumorigenesis and immune evolution.
Author Correction: The repertoire of mutational signatures in human cancer
Author Correction: Pan-cancer analysis of whole genomes.
Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers
Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers.
The repertoire of mutational signatures in human cancer
The repertoire of mutational signatures in human cancer.
Pan-cancer analysis of whole genomes.
Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types.
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
Genomic profiling reveals mutational landscape in parathyroid carcinomas
Regulatory crosstalk between lineage-survival oncogenes <i>KLF5, GATA4</i> and <i>GATA6</i> cooperatively promotes gastric cancer development
Whole-Exome Sequencing Studies of Parathyroid Carcinomas Reveal Novel<i>PRUNE2</i>Mutations, Distinctive Mutational Spectra Related to APOBEC-Catalyzed DNA Mutagenesis and Mutational Enrichment in Kinases Associated With Cell Migration and Invasion
Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers
Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
Exome sequencing of liver fluke–associated cholangiocarcinoma