Area of research
Pathology and Forensic Medicine · Immunology
Research interest
Research interests include Biology, Cancer research, Exome sequencing, Lymphoma, Carcinogenesis, and ARID1A.
Priming with DNMT Inhibitors Potentiates PD-1 Immunotherapy by Triggering Viral Mimicry in Relapsed/Refractory NK/T-cell Lymphoma
Single‐Cell Analysis Reveals Malignant Cells Reshape the Cellular Landscape and Foster an Immunosuppressive Microenvironment of Extranodal NK/T‐Cell Lymphoma
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma
An ex vivo platform to guide drug combination treatment in relapsed/refractory lymphoma
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations
Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2
<i>VHL</i> Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma
JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma
Genomic landscapes of breast fibroepithelial tumors
Disruption of tubular Flcn expression as a mouse model for renal tumor induction
Regulatory crosstalk between lineage-survival oncogenes <i>KLF5, GATA4</i> and <i>GATA6</i> cooperatively promotes gastric cancer development
Whole-Exome Sequencing Studies of Parathyroid Carcinomas Reveal Novel<i>PRUNE2</i>Mutations, Distinctive Mutational Spectra Related to APOBEC-Catalyzed DNA Mutagenesis and Mutational Enrichment in Kinases Associated With Cell Migration and Invasion
Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers
Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
Exome sequencing of liver fluke–associated cholangiocarcinoma