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Dachuan Huang

National University of Singapore · SG
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Area of research
Pathology and Forensic Medicine · Immunology
Research interest
Research interests include Biology, Cancer research, Exome sequencing, Lymphoma, Carcinogenesis, and ARID1A.
h-index
citations
3,373
works
19
NIH funding
primary concept
email

Recent publications

Priming with DNMT Inhibitors Potentiates PD-1 Immunotherapy by Triggering Viral Mimicry in Relapsed/Refractory NK/T-cell Lymphoma
Cancer Discovery 2025cited by 6position: middledoi
Single‐Cell Analysis Reveals Malignant Cells Reshape the Cellular Landscape and Foster an Immunosuppressive Microenvironment of Extranodal NK/T‐Cell Lymphoma
Advanced Science 2023cited by 27position: middledoi
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma
Nature Cell Biology 2023cited by 24position: middledoi
An ex vivo platform to guide drug combination treatment in relapsed/refractory lymphoma
Science Translational Medicine 2022cited by 37position: middledoi
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
Journal of Clinical Investigation 2020cited by 105position: middledoi
Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma
Leukemia 2020cited by 79position: middledoi
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
Nature Communications 2020cited by 48position: middledoi
Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations
The Lancet Oncology 2019cited by 70position: middledoi
Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2
Science Translational Medicine 2017cited by 210position: middledoi
<i>VHL</i> Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma
Cancer Discovery 2017cited by 182position: middledoi
JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma
Leukemia 2016cited by 148position: middledoi
Genomic landscapes of breast fibroepithelial tumors
Nature Genetics 2015cited by 214position: middledoi
Disruption of tubular Flcn expression as a mouse model for renal tumor induction
Kidney International 2015cited by 35position: middledoi
Regulatory crosstalk between lineage-survival oncogenes <i>KLF5, GATA4</i> and <i>GATA6</i> cooperatively promotes gastric cancer development
Gut 2014cited by 172position: middledoi
Whole-Exome Sequencing Studies of Parathyroid Carcinomas Reveal Novel<i>PRUNE2</i>Mutations, Distinctive Mutational Spectra Related to APOBEC-Catalyzed DNA Mutagenesis and Mutational Enrichment in Kinases Associated With Cell Migration and Invasion
The Journal of Clinical Endocrinology & Metabolism 2014cited by 106position: middledoi
Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers
Nature Genetics 2013cited by 494position: middledoi
Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool
Science Translational Medicine 2013cited by 289position: middledoi
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
Nature Genetics 2012cited by 635position: middledoi
Exome sequencing of liver fluke–associated cholangiocarcinoma
Nature Genetics 2012cited by 492position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Bin Tean Teh · SingHealth Duke-NUS Academic Medical Centre3 papers (2014–2025)Choon Kiat Ong · Duke-NUS Medical School2 papers (2014–2025)Steve Rozen · Chang Gung University2 papers (2014–2014)Willie Yu · Duke-NUS Medical School2 papers (2014–2014)Anna Gan · National University of Singapore2 papers (2014–2014)Patrick Tan · Duke-NUS Medical School2 papers (2014–2014)Tom van Wezel · Leiden University Medical Center1 papers (2014–2014) · 1 papers (2014–2014)Guan Wu · University of Rochester Medical Center1 papers (2015–2015)Bart O. Williams · University of Arizona1 papers (2015–2015) · 1 papers (2014–2014)Soon Thye Lim · Duke-NUS Medical School1 papers (2025–2025)Jing Quan Lim · Agency for Science, Technology and Research1 papers (2025–2025)Jason Yongsheng Chan · National University of Singapore1 papers (2025–2025)Niantao Deng · National University of Singapore1 papers (2014–2014)Zhongfa Zhang · Shandong University1 papers (2015–2015) · 1 papers (2025–2025) · 1 papers (2014–2014)Xian Zeng · Sun Yat-sen University1 papers (2025–2025) · 1 papers (2014–2014)
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