Area of research
Pathology and Forensic Medicine · Gastroenterology
Research interest
Research focused on Opisthorchis viverrini and Exome sequencing, with related work in ARID1A, Colorectal cancer, DNA. Notable publications include 'Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes', 'Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers', and 'Exome sequencing of liver fluke–associated cholangiocarcinoma'.
A deep-learning model for quantifying circulating tumour DNA from the density distribution of DNA-fragment lengths
Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer
Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden
Regulatory crosstalk between lineage-survival oncogenes <i>KLF5, GATA4</i> and <i>GATA6</i> cooperatively promotes gastric cancer development
Whole-Exome Sequencing Studies of Parathyroid Carcinomas Reveal Novel<i>PRUNE2</i>Mutations, Distinctive Mutational Spectra Related to APOBEC-Catalyzed DNA Mutagenesis and Mutational Enrichment in Kinases Associated With Cell Migration and Invasion
Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers
Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
Exome sequencing of liver fluke–associated cholangiocarcinoma