Area of research
Oncology · Molecular Biology
Research interest
Research interests include Pancreatic and Hepatic Oncology Research, Epigenetics and DNA Methylation, Cancer Cells and Metastasis, and Cancer Genomics and Diagnostics.
Epigenetic dysregulation of IRF9 drives excessive interferon signaling in COPD
Site-specific activation of the proton pump inhibitor rabeprazole by tetrathiolate zinc centres
Author Reply to Peer Reviews of Epigenetic dysregulation of IRF9 drives excessive interferon signalling in COPD
The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells
LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma
HAPLN1 potentiates peritoneal metastasis in pancreatic cancer
Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
Epigenetic deregulation of IFN and WNT pathways in AT2 cells impairs alveolar regeneration (in COPD)
Molecular heterogeneity and commonalities in pancreatic cancer precursors with gastric and intestinal phenotype
Practical Considerations for Complex Tissue Dissociation for Single-Cell Transcriptomics
Selenocysteine metabolism is a targetable vulnerability in <i>MYCN</i> -amplified cancers
HAPLN1 is a driver for peritoneal carcinomatosis in pancreatic cancer
Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis
On the Origin of Pancreatic Cancer: Molecular Tumor Subtypes in Perspective of Exocrine Cell Plasticity
Stromal NRG1 in luminal breast cancer defines pro-fibrotic and migratory cancer-associated fibroblasts
Versatile workflow for cell type–resolved transcriptional and epigenetic profiles from cryopreserved human lung
New Insights Into Pancreatic Cancer: Notes from a Virtual Meeting
Human Retrotransposons and the Global Shutdown of Homeostatic Innate Immunity by Oncolytic Parvovirus H-1PV in Pancreatic Cancer
Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin
Novel Non-integrating DNA Nano-S/MAR Vectors Restore Gene Function in Isogenic Patient-Derived Pancreatic Tumor Models
Maintenance of epithelial traits and resistance to mesenchymal reprogramming promote proliferation in metastatic breast cancer
Stromal NRG1 in luminal breast cancer defines pro-fibrotic and migratory cancer-associated fibroblasts
Versatile workflow for cell type resolved transcriptional and epigenetic profiles from cryopreserved human lung
Versatile workflow for storage, characterization and cell-type resolved transcriptional and epigenetic profiles of human lung samples (LSC-2020)
Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors
Endothelial Notch1 Activity Facilitates Metastasis
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma
Identification and Validation of Novel Subtype-Specific Protein Biomarkers in Pancreatic Ductal Adenocarcinoma
Abstract IA22: CYP3A5 mediates resistance to small molecule inhibitors in a subtype of pancreatic ductal adenocarcinoma
Abstract B77: CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma