Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include MicroRNA in disease regulation, RNA Research and Splicing, RNA and protein synthesis mechanisms, and Genomics and Phylogenetic Studies.
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances
A genome resource for the marine annelid Platynereis spp
A Senescent Cluster in Aged Human Hematopoietic Stem Cell Compartment as Target for Senotherapy
Genetic lesions in nodular lymphocyte-predominant Hodgkin lymphoma and T cell/histiocyte-rich large B-cell lymphoma identified by whole genome sequencing
Integrative spatial and multi-omic profiling in bladder cancer links L1 retrotransposition to extrachromosomal DNA, genomic instability, and viral mimicry response
Author Reply to Peer Reviews of Epigenetic dysregulation of IRF9 drives excessive interferon signalling in COPD
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells
Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress
Evolution of SARS-CoV-2 in the Rhine-Neckar/Heidelberg Region 01/2021 – 07/2023
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia
High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD
RNA-sequencing based first choice of treatment and determination of risk in multiple myeloma
Epigenetic deregulation of IFN and WNT pathways in AT2 cells impairs alveolar regeneration (in COPD)
A faecal microbiota signature with high specificity for pancreatic cancer
Drivers and determinants of strain dynamics following fecal microbiota transplantation
Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection
Neutralizing antibody response against the B.1.617.2 (delta) and the B.1.1.529 (omicron) variants after a third mRNA SARS-CoV-2 vaccine dose in kidney transplant recipients
Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency–Associated Villous Atrophy and Norovirus Infection
Impact of high platelet turnover on the platelet transcriptome: Results from platelet RNA-sequencing in patients with sepsis
Integrated genomic analysis reveals actionable targets in pediatric spinal cord low-grade gliomas
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia
Targeted parallel <scp>DNA</scp> sequencing detects circulating tumor‐associated variants of the mitochondrial and nuclear genomes in patients with neuroblastoma
3019 – SINGLE-CELL PROTEO-GENOMIC REFERENCE MAPS OF THE HEMATOPOIETIC SYSTEM ENABLE THE PURIFICATION AND MASSIVE PROFILING OF PRECISELY DEFINED CELL STATES
High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD phenotypes in human lung fibroblasts
High-resolution transcriptomic and epigenetic profiling across disease stages identifies novel regulators of COPD phenotypes.
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states
The expansion of human T-bet <sup>high</sup> CD21 <sup>low</sup> B cells is T cell dependent
Single‐cell transcriptomics reveals immune response of intestinal cell types to viral infection
AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia
Surgical treatment of brainstem cavernous malformations: an international Delphi consensus