Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Single-cell and spatial transcriptomics, RNA modifications and cancer, Cancer Genomics and Diagnostics, and RNA Research and Splicing.
Conserved transcriptional regulation by BRN1 and BRN2 in neocortical progenitors drives mammalian neural specification and neocortical expansion
Psychedelics reopen the social reward learning critical period
<i>Ret</i> deficiency decreases neural crest progenitor proliferation and restricts fate potential during enteric nervous system development
Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS
Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry
Universal prediction of cell-cycle position using transfer learning
Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection
An in vivo screen of noncoding loci reveals that <i>Daedalus</i> is a gatekeeper of an Ikaros-dependent checkpoint during haematopoiesis
Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development
Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus
Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification
Linear models enable powerful differential activity analysis in massively parallel reporter assays
Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species
Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution
Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing
Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells
Enter the Matrix: Factorization Uncovers Knowledge from Omics
Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease
Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA
The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan
A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome
Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre
DeCoN: Genome-wide Analysis of In Vivo Transcriptional Dynamics during Pyramidal Neuron Fate Selection in Neocortex
Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons
Multiple knockout mouse models reveal lincRNAs are required for life and brain development
DNMT1-interacting RNAs block gene-specific DNA methylation
Long noncoding RNAs regulate adipogenesis
The MicroRNA miR-181 Is a Critical Cellular Metabolic Rheostat Essential for NKT Cell Ontogenesis and Lymphocyte Development and Homeostasis
Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks