Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Epigenetics and DNA Methylation, Metabolism, Diabetes, and Cancer, and Cancer Immunotherapy and Biomarkers.
Activated ATF6α is a hepatic tumour driver restricting immunosurveillance
l-2-Hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression
Aspartate signalling drives lung metastasis via alternative translation
High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non–Small Cell Lung Cancer in Patients
Mitochondrial Glutathione Import Enables Breast Cancer Metastasis via Integrated Stress Response Signaling
Constitutive expression of the transcriptional co-activator IκBζ promotes melanoma growth and immunotherapy resistance
Amitriptyline inhibits Plasmodium development in infected red blood cells by modulating sphingolipid metabolism and glucose uptake
Sex-specific survival in advanced metastatic melanoma – a DeCOG study on 2032 patients of the multicenter prospective skin cancer registry ADOREG
Presence of brain metastasis differentially impacts long-term survival after first-line therapy in melanoma depending on BRAF mutation status
Outcome of systemic therapy in patients with advanced rare skin cancers: A retrospective multicenter DeCOG study of 209 patients
Redirecting resistance evolution in <i> BRAF <sup>V600</sup> </i> melanoma by inhibition of the peroxiredoxin-thioredoxin system
De novo and salvage purine synthesis pathways across tissues and tumors
Short-term post-fast refeeding enhances intestinal stemness via polyamines
Cranioencephalic functional lymphoid units in glioblastoma
Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis
Retrotransposons are co-opted to activate hematopoietic stem cells and erythropoiesis
Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity
Early versus late response to PD-1-based immunotherapy in metastatic melanoma
Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma
Changes in tumor and cardiac metabolism upon immune checkpoint
Correlation of tumor PD-L1 expression in different tissue types and outcome of PD-1-based immunotherapy in metastatic melanoma – analysis of the DeCOG prospective multicenter cohort study ADOREG/TRIM
Characterisation and outcome of RAC1 mutated melanoma
Combined immunotherapy with ipilimumab plus nivolumab in metastatic <scp>PD‐1</scp>/<scp>PD‐L1</scp>‐refractory Merkel cell carcinoma—a case report
Prognostic factors in the primary care of patients with Merkel cell carcinoma: A monocentric cohort study of 108 patients from a tertiary referral centre
1168P Tumor PD-L1 predicts the outcome of PD-1-based immunotherapy in metastatic melanoma depending on the type of tissue examined
Compartmentalized metabolism supports midgestation mammalian development
Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells
In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors
A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis