Area of research
Organic Chemistry · Molecular Biology
Research interest
Research interests include Click Chemistry and Applications, Fluorine in Organic Chemistry, Chemical Synthesis and Analysis, and Peptidase Inhibition and Analysis.
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D
Abstract B102: Development of covalent inhibitors targeting Ras Q61 hotspot mutants
Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes
KRAS is vulnerable to reversible switch-II pocket engagement in cells
Drugging the Next Undruggable KRAS Allele-Gly12Asp
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
The growing applications of SuFEx click chemistry
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides