Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Genetic Mapping and Diversity in Plants and Animals, Genetic and phenotypic traits in livestock, and Bioinformatics and Genomic Networks.
Human and bacterial genetic variation shape oral microbiomes and health
Insights into DNA repeat expansions among 900,000 biobank participants
The DNA virome varies with human genes and environments
The Somatic Mosaicism across Human Tissues Network
Protein-altering variants at copy number-variable regions influence diverse human phenotypes
Clonal haematopoiesis and risk of chronic liver disease
Repeat polymorphisms underlie top genetic risk loci for glaucoma and colorectal cancer
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions
The lingering effects of Neanderthal introgression on human complex traits
Author Correction: Clonal haematopoiesis and risk of chronic liver disease
Genome-wide mapping of somatic mutation rates uncovers drivers of cancer
Influences of rare copy-number variation on human complex traits
A spectrum of recessiveness among Mendelian disease variants in UK Biobank
Schizophrenia-associated somatic copy number variants from 12,834 cases reveal contribution to risk and recurrent, isoform-specific <i>NRXN1</i> disruptions
Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection
Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets
Large mosaic copy number variations confer autism risk
A model and test for coordinated polygenic epistasis in complex traits
Fast, sensitive and accurate integration of single-cell data with Harmony
Genetic predisposition to mosaic Y chromosome loss in blood
Genes with High Network Connectivity Are Enriched for Disease Heritability
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
Leveraging Polygenic Functional Enrichment to Improve GWAS Power
Mixed-model association for biobank-scale datasets
Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases
Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits
Estimating cross‐population genetic correlations of causal effect sizes
Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk