Area of research
Molecular Biology · Epidemiology
Research interest
Research interests include Developmental Biology and Gene Regulation, Epigenetics and DNA Methylation, PI3K/AKT/mTOR signaling in cancer, and Autophagy in Disease and Therapy.
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer
Balancing lysosome abundance in health and disease
Altered propionate metabolism contributes to tumour progression and aggressiveness
Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1
Age-induced accumulation of methylmalonic acid promotes tumour progression
Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation
Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ