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Yi‐Hsiang Hsu

Broad Institute · US
Area of research
Genetics · Orthopedics and Sports Medicine
Research interest
Research interests include Genetic Associations and Epidemiology, Bone health and osteoporosis research, Bone Metabolism and Diseases, and Nutrition, Genetics, and Disease.
h-index
41
citations
8,546
works
149
NIH funding
primary concept
Medicine
email

Recent publications

Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder
Translational Psychiatry 2024cited by 13position: middledoi
Plasma proteomic associations with genetics and health in the UK Biobank
Nature 2023cited by 1,424position: middledoi
Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder
Molecular Psychiatry 2023cited by 39position: middledoi
Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach
The British Journal of Psychiatry 2022cited by 40position: middledoi
Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients
Translational Psychiatry 2021cited by 59position: middledoi
A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density
Cell Metabolism 2021cited by 52position: middledoi
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
Molecular Psychiatry 2020cited by 94position: middledoi
Metabolomics Insights into Osteoporosis Through Association With Bone Mineral Density
Journal of Bone and Mineral Research 2020cited by 69position: middledoi
Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry
Journal of Bone and Mineral Research 2019cited by 41position: firstdoi
An atlas of genetic influences on osteoporosis in humans and mice
Nature Genetics 2018cited by 826position: middledoi
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
The American Journal of Human Genetics 2018cited by 452position: middledoi
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
Nature Communications 2018cited by 396position: middledoi
Meta-analysis of epigenome-wide association studies of cognitive abilities
Molecular Psychiatry 2018cited by 96position: middledoi
Disentangling the genetics of lean mass
American Journal of Clinical Nutrition 2018cited by 47position: middledoi
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
Nature Communications 2017cited by 227position: middledoi
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
Nature Communications 2017cited by 186position: middledoi
Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder
JAMA Psychiatry 2017cited by 148position: middledoi
Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis
The American Journal of Human Genetics 2017cited by 136position: middledoi
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
Nature Communications 2017cited by 96position: middledoi
Epigenome-wide Association of DNA Methylation in Whole Blood With Bone Mineral Density
Journal of Bone and Mineral Research 2017cited by 58position: middledoi
Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
Nature Communications 2017cited by 9position: middledoi
A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of Brodalumab in Patients With Moderate-to-Severe Crohn’s Disease
The American Journal of Gastroenterology 2016cited by 367position: middledoi
<scp>GWAS</scp> analysis of handgrip and lower body strength in older adults in the <scp>CHARGE</scp> consortium
Aging Cell 2016cited by 64position: middledoi
A combined reference panel from the 1000 Genomes and UK10K projects improved rare variant imputation in European and Chinese samples
Scientific Reports 2016cited by 51position: lastdoi
Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of <i>SLC1A3</i> and <i>EPHB2</i>
Journal of Bone and Mineral Research 2016cited by 46position: lastdoi
<i>FTO</i> Obesity Variant Circuitry and Adipocyte Browning in Humans
New England Journal of Medicine 2015cited by 1,384position: middledoi
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
Nature 2015cited by 625position: middledoi
Environmental Mold and Mycotoxin Exposures Elicit Specific Cytokine and Chemokine Responses
PLoS ONE 2015cited by 30position: middledoi
Individual and Joint Associations of Methylenetetrahydrofolate Reductase C677T Genotype and Plasma Homocysteine With Dyslipidemia in a Chinese Population With Hypertension
Clinical and Applied Thrombosis/Hemostasis 2015cited by 13position: middledoi
Pleiotropic genes for metabolic syndrome and inflammation
Molecular Genetics and Metabolism 2014cited by 147position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Douglas P. Kiel · Harvard University4 papers (2016–2021)Isabel Sousa · Hospital do Divino Espírito Santo2 papers (2015–2021)Hans Hauner · Technical University of Munich2 papers (2015–2021)David Karasik · Gladstone Institutes2 papers (2016–2021) · 2 papers (2015–2021)Shanqun Jiang · Anhui Medical University2 papers (2013–2015) · 2 papers (2015–2021) · 2 papers (2013–2016)J. Brent Richards · University of London2 papers (2016–2017) · 2 papers (2013–2015)Melina Claussnitzer · Broad Institute2 papers (2015–2021)Clifford J. Rosen · Maine Medical Center2 papers (2014–2021)Xiping Xu · University of Illinois Chicago2 papers (2013–2015)Roby Joehanes · University of Alabama at Birmingham1 papers (2017–2017)Jonathan K. Pritchard · Stanford Medicine1 papers (2021–2021) · 1 papers (2016–2016)Hou‐Feng Zheng · Fudan University1 papers (2016–2016)Nezar Abdennur · Massachusetts Institute of Technology1 papers (2015–2015)Daniel J. Drucker · Toronto Public Health1 papers (2015–2015)Gil Melmed · Cedars-Sinai Smidt Heart Institute1 papers (2016–2016)