Area of research
Genetics · Physiology
Research interest
Research interests include Alzheimer's disease research and treatments, Genetic Associations and Epidemiology, Bioinformatics and Genomic Networks, and Dementia and Cognitive Impairment Research.
Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels
Plasma amyloid β levels are driven by genetic variants near <i>APOE, BACE1, APP, PSEN2</i>: A genome‐wide association study in over 12,000 non‐demented participants
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Analysis of shared heritability in common disorders of the brain
Association of branched‐chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts
Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease
Novel genetic loci associated with hippocampal volume
Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function
Incidence of Dementia over Three Decades in the Framingham Heart Study
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer’s Disease
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease
Plasma clusterin levels and risk of dementia, Alzheimer's disease, and stroke
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)
A novel Alzheimer disease locus located near the gene encoding tau protein
Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI
GWAS for executive function and processing speed suggests involvement of the CADM2 gene
Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease
Convergent genetic and expression data implicate immunity in Alzheimer's disease
Genetics of Alzheimer’s Disease
Genome-wide association study of kidney function decline in individuals of European descent
Plasma amyloid‐β and risk of Alzheimer's disease in the Framingham Heart Study
Follow-up of loci from the International Genomics of Alzheimer’s Disease Project identifies TRIP4 as a novel susceptibility gene
Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium
SUCLG2 identified as both a determinator of CSF Aβ1–42 levels and an attenuator of cognitive decline in Alzheimer's disease
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease