Area of research
Physiology · Genetics
Research interest
Research interests include Alzheimer's disease research and treatments, Genetic Associations and Epidemiology, Bioinformatics and Genomic Networks, and Dementia and Cognitive Impairment Research.
First genome-wide association study reveals immune-mediated aetiopathology in idiopathic achalasia
Neuroinflammation in Alzheimer disease
The Alzheimer’s disease risk gene BIN1 regulates activity-dependent gene expression in human-induced glutamatergic neurons
Genetic risk factors underlying white matter hyperintensities and cortical atrophy
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models
Association of Rare <i>APOE</i> Missense Variants V236E and R251G With Risk of Alzheimer Disease
Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels
Association of <i>APOE</i> -Independent Alzheimer Disease Polygenic Risk Score With Brain Amyloid Deposition in Asymptomatic Older Adults
Plasma amyloid β levels are driven by genetic variants near <i>APOE, BACE1, APP, PSEN2</i>: A genome‐wide association study in over 12,000 non‐demented participants
Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer’s disease etiopathogenesis
Contribution of rare and predicted pathogenic gene variants to childhood-onset lupus: a large, genetic panel analysis of British and French cohorts
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study
K-Stacker: an algorithm to hack the orbital parameters of planets hidden in high-contrast imaging
Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by <i>APOE</i> Genotype
Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation
Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease
Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function
Developmental Expression of 4-Repeat-Tau Induces Neuronal Aneuploidy in Drosophila Tauopathy Models
Prevalence, awareness, treatment, and control of hypertension in older people in Central Africa: the EPIDEMCA study
Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease
Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy
Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer’s Disease
Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium
Common polygenic variation enhances risk prediction for Alzheimer’s disease
Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes
Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease