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Kam W. Leong

Universidad de Santiago de Chile · CL
Area of research
Molecular Biology · Biomedical Engineering
Research interest
Research interests include RNA Interference and Gene Delivery, Advanced biosensing and bioanalysis techniques, 3D Printing in Biomedical Research, and Electrospun Nanofibers in Biomedical Applications.
h-index
132
citations
63,355
works
842
NIH funding
primary concept
email

Recent publications

Incorporation of polylactic acid microplastics into the carbon cycle as a carbon source to remodel the endogenous metabolism of the gut
Proceedings of the National Academy of Sciences 2025cited by 42position: middledoi
Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor–immune hubs
Nature Biotechnology 2024cited by 52position: middledoi
Intestinal Epithelial Serotonin as a Novel Target for Treating Disorders of Gut-Brain Interaction and Mood
Gastroenterology 2024cited by 37position: middledoi
FcRn-dependent IgG accumulation in adipose tissue unmasks obesity pathophysiology
Cell Metabolism 2024cited by 26position: middledoi
Tackling Severe Neutrophilic Inflammation in Airway Disorders with Functionalized Nanosheets
ACS Nano 2024cited by 23position: middledoi
PAR2 on oral cancer cells and nociceptors contributes to oral cancer pain that can be relieved by nanoparticle-encapsulated AZ3451
Biomaterials 2024cited by 20position: middledoi
Modulation of Unregulated Inflammation‐Associated Coagulopathy in Sepsis Using Multifunctional Nanosheets
Advanced Functional Materials 2024cited by 18position: middledoi
Spatial epigenome–transcriptome co-profiling of mammalian tissues
Nature 2023cited by 405position: middledoi
Circulating Cell‐Free DNAs as a Biomarker and Therapeutic Target for Acetaminophen‐Induced Liver Injury
Advanced Science 2023cited by 32position: middledoi
Focused ultrasound–mediated brain genome editing
Proceedings of the National Academy of Sciences 2023cited by 32position: lastdoi
Phenylboronic Acid-Functionalized Polyplexes Tailored to Oral CRISPR Delivery
Nano Letters 2023cited by 30position: lastdoi
Leveraging efferocytosis blockade for improved cancer chemo-immunotherapy through synchronized release of doxorubicin and BMS777607 confined within tailored mesoporous silica nanoparticles
Nano Today 2023cited by 18position: middledoi
Spatial profiling of chromatin accessibility in mouse and human tissues
Nature 2022cited by 348position: middledoi
A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease
Science Advances 2022cited by 222position: middledoi
Nanoparticulate cell-free DNA scavenger for treating inflammatory bone loss in periodontitis
Nature Communications 2022cited by 132position: lastdoi
An Injectable Antibiotic Hydrogel that Scavenges Proinflammatory Factors for the Treatment of Severe Abdominal Trauma
Advanced Functional Materials 2022cited by 88position: middledoi
Selective targeting of visceral adiposity by polycation nanomedicine
Nature Nanotechnology 2022cited by 56position: middledoi
Polycationic PAMAM ameliorates obesity-associated chronic inflammation and focal adiposity
Biomaterials 2022cited by 27position: middledoi
The NIH Somatic Cell Genome Editing program
Nature 2021cited by 129position: middledoi
A Versatile and Robust Platform for the Scalable Manufacture of Biomimetic Nanovaccines
Advanced Science 2021cited by 84position: lastdoi
Nanotechnology for pain management: Current and future therapeutic interventions
Nano Today 2021cited by 80position: lastdoi
A materials-science perspective on tackling COVID-19
Nature Reviews Materials 2020cited by 302position: middledoi
Light: A Magical Tool for Controlled Drug Delivery
Advanced Functional Materials 2020cited by 298position: lastdoi
Treatment of severe sepsis with nanoparticulate cell-free DNA scavengers
Science Advances 2020cited by 182position: middledoi
Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects
Science Advances 2020cited by 163position: middledoi
Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain
Proceedings of the National Academy of Sciences 2020cited by 105position: middledoi
A Versatile Nonviral Delivery System for Multiplex Gene‐Editing in the Liver
Advanced Materials 2020cited by 77position: lastdoi
Flash technology-based self-assembly in nanoformulation: Fabrication to biomedical applications
Materials Today 2020cited by 62position: lastdoi
Identification of Specific Joint-Inflammatogenic Cell-Free DNA Molecules From Synovial Fluids of Patients With Rheumatoid Arthritis
Frontiers in Immunology 2020cited by 45position: middledoi
Engineering Cell Membrane‐Based Nanotherapeutics to Target Inflammation
Advanced Science 2019cited by 235position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Mingqiang Li · Southwest University of Science and Technology13 papers (2018–2023)Yeh‐Hsing Lao · Columbia University12 papers (2015–2024)Dan Shao · State Key Laboratory of Oral Diseases11 papers (2019–2023)Yongming Chen · Sun Yat-sen University9 papers (2015–2020)Hai‐Quan Mao · Johns Hopkins University9 papers (2014–2020)Lixin Liu · Shanghai University8 papers (2017–2020)Hanze Hu · Columbia University8 papers (2019–2022)Hon Fai Chan · Chinese University of Hong Kong6 papers (2012–2020)Zhiyu He · Northeastern University5 papers (2017–2019)Houkuan Tian · Zhejiang Sci-Tech University4 papers (2017–2018)Yang Xiao · Chongqing Cancer Hospital4 papers (2022–2024)Zhijia Liu · Kunming University of Science and Technology4 papers (2018–2019)Jianati Dawulieti · Jilin University4 papers (2020–2022)Chao Yang · Hebei Agricultural University4 papers (2020–2022)Nigel W. Bunnett · New York Proton Center3 papers (2020–2024)Yizong Hu · Massachusetts Institute of Technology3 papers (2017–2019)Baoding Huang · Third Affiliated Hospital of Southern Medical University3 papers (2022–2022)Madi Sun · Jilin University3 papers (2020–2023)Zhaoxu Tu · Nanchang University3 papers (2021–2024)Farshid Guilak · Washington University in St. Louis3 papers (2013–2015)