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Farshid Guilak

Washington University in St. Louis · US
Area of research
Rheumatology · Surgery
Research interest
Research interests include Osteoarthritis Treatment and Mechanisms, Knee injuries and reconstruction techniques, Tendon Structure and Treatment, and Total Knee Arthroplasty Outcomes.
h-index
126
citations
52,579
works
665
NIH funding
primary concept
email

Recent publications

Adipose-derived leptin and complement factor D mediate osteoarthritis severity and pain
Science Advances 2025cited by 21position: lastdoi
Osteoarthritis as a systemic disease
Nature Reviews Rheumatology 2025cited by 12position: lastdoi
Engineered self-regulating macrophages for targeted anti-inflammatory drug delivery
Arthritis Research & Therapy 2024cited by 11position: lastdoi
Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes
Proceedings of the National Academy of Sciences 2023cited by 70position: lastdoi
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes
eLife 2023cited by 22position: lastdoi
Perlecan in Pericellular Mechanosensory Cell-Matrix Communication, Extracellular Matrix Stabilisation and Mechanoregulation of Load-Bearing Connective Tissues
International Journal of Molecular Sciences 2021cited by 68position: firstdoi
Fresh Osteochondral and Chondral Allograft Preservation and Storage Media: A Systematic Review of the Literature
The American Journal of Sports Medicine 2021cited by 25position: middledoi
Intra-articular depletion of macrophages increases acute synovitis and alters macrophage polarity in the injured mouse knee
Osteoarthritis and Cartilage 2020cited by 65position: middledoi
<sup/> CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments
Tissue Engineering Part A 2017cited by 95position: middledoi
Canine hip dysplasia: A natural animal model for human developmental dysplasia of the hip
Journal of Orthopaedic Research® 2017cited by 65position: middledoi
Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research
Journal of Biomechanical Engineering 2017cited by 19position: middledoi
3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures
Advanced Materials 2015cited by 857position: middledoi
Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
Journal of Clinical Investigation 2015cited by 188position: middledoi
Type VI Collagen Regulates Pericellular Matrix Properties, Chondrocyte Swelling, and Mechanotransduction in Mouse Articular Cartilage
Arthritis & Rheumatology 2015cited by 174position: lastdoi
Non-invasive mouse models of post-traumatic osteoarthritis
Osteoarthritis and Cartilage 2015cited by 140position: middledoi
3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures (Adv. Mater. 27/2015)
Advanced Materials 2015cited by 98position: middledoi
A vision on the future of articular cartilage repair
European Cells and Materials 2014cited by 74position: middledoi
RNA-guided gene activation by CRISPR-Cas9–based transcription factors
Nature Methods 2013cited by 1,343position: middledoi
Pain coping skills training and lifestyle behavioral weight management in patients with knee osteoarthritis: A randomized controlled study
Pain 2012cited by 180position: middledoi
Multiscale Mechanics of Articular Cartilage: Potentials and Challenges of Coupling Musculoskeletal, Joint, and Microscale Computational Models
Annals of Biomedical Engineering 2012cited by 78position: middledoi
Altered Trabecular Bone Structure and Delayed Cartilage Degeneration in the Knees of Collagen VI Null Mice
PLoS ONE 2012cited by 73position: lastdoi

Grants

EAGER: Regulation of Cartilage Mechanobiology by Hydrostatic Pressure
NSF1638442$177,0762016–2017PIRePORTER
EAGER: Regulation of Cartilage Mechanobiology by Hydrostatic Pressure
NSF1445792$267,0002014–2016PIRePORTER

Frequent collaborators

Kelsey H. Collins · University of California, San Francisco3 papers (2024–2025)Kam W. Leong · Universidad de Santiago de Chile3 papers (2013–2015)Wolfgang Liedtke · Nippon Paint (Japan)3 papers (2015–2023) · 3 papers (2023–2025) · 2 papers (2012–2020)Christine T. N. Pham · University of Toronto2 papers (2024–2025)Xuanhe Zhao · Massachusetts Institute of Technology2 papers (2015–2015) · 2 papers (2012–2015)Ahmet Erdemir · Cleveland Clinic Lerner College of Medicine2 papers (2012–2017) · 2 papers (2015–2020)Dalton G. Sycks · Boston Consulting Group (United States)2 papers (2015–2015) · 2 papers (2023–2023)Nicole A. Zelenski · Emory University2 papers (2012–2015)Pratiksha I. Thakore · Broad Institute2 papers (2013–2017)Gabriel P. López · University of New Mexico2 papers (2015–2015)Sungmin Hong · Kyung Hee University2 papers (2015–2015)Hon Fai Chan · Chinese University of Hong Kong2 papers (2015–2015)Shaoting Lin · Michigan State University2 papers (2015–2015)Kristin L. Lenz · University of Missouri2 papers (2024–2025)Charles A. Gersbach · Duke University2 papers (2013–2017)