Area of research
Neurology · Physiology
Research interest
Research interests include Alzheimer's disease research and treatments, Amyotrophic Lateral Sclerosis Research, Parkinson's Disease Mechanisms and Treatments, and Neurological diseases and metabolism.
Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer’s disease
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases
Chemical imaging delineates Aβ plaque polymorphism across the Alzheimer’s disease spectrum
Direct interaction between TDP-43 and Tau promotes their co-condensation, while suppressing Tau fibril formation and seeding
Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration
DNA methylation as a contributor to dysregulation of STX6 and other frontotemporal Lobar degeneration genetic risk-associated loci
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer’s disease neuropathology
Tau protein profiling in tauopathies: a human brain study
MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study
Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
Author Correction: Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer’s disease models
Microglia‐synapse engulfment via PtdSer‐TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models
Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
Structures of α-synuclein filaments from human brains with Lewy pathology
Medin co-aggregates with vascular amyloid-β in Alzheimer’s disease
Mitochondrial dysfunction is a key pathological driver of early stage Parkinson’s
Brain region-specific susceptibility of Lewy body pathology in synucleinopathies is governed by α-synuclein conformations
N-terminally truncated Aβ4-x proteoforms and their relevance for Alzheimer’s pathophysiology
Imaging tau pathology in Alzheimer’s disease with positron emission tomography: lessons learned from imaging-neuropathology validation studies
Correlative Chemical Imaging Identifies Amyloid Peptide Signatures of Neuritic Plaques and Dystrophy in Human Sporadic Alzheimer's Disease
Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals <i>OTUD4</i> in shared dysregulated signatures across pathological subtypes
Structure-based classification of tauopathies
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
P‐tau235: a novel biomarker for staging preclinical Alzheimer’s disease
Transcriptomic analysis of frontotemporal lobar degeneration with TDP-43 pathology reveals cellular alterations across multiple brain regions
Discriminatory ability of next-generation tau PET tracers for Alzheimer’s disease
The association of circulating amylin with β‐amyloid in familial Alzheimer's disease
Variability in the type and layer distribution of cortical Aβ pathology in familial Alzheimer’s disease
Common ALS/FTD risk variants in <i>UNC13A</i> exacerbate its cryptic splicing and loss upon TDP-43 mislocalization