Area of research
Public Health, Environmental and Occupational Health · Genetics
Research interest
Research interests include Malaria Research and Control, Estrogen and related hormone effects, Cancer Treatment and Pharmacology, and Computational Drug Discovery Methods.
Antitrypanosomal Chloronitrobenzamides
Optimization of diastereomeric dihydropyridines as antimalarials
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia.
Optimization of Orally Bioavailable Antileishmanial 2,4,5-Trisubstituted Benzamides
Author Correction: Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia.
Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M.
Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents
Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones
Synthesis and Structure-Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-<i>b</i>]pyridines.
Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones
A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML.
Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation.
Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway.
Discovery of an Orally Bioavailable Inhibitor of Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation
Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation
Oxazole and Thiazole Analogs of Sulindac for Cancer Prevention
A small diversity library of α-methyl amide analogs of sulindac for probing anticancer structure-activity relationships
Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase
Diverse amide analogs of sulindac for cancer treatment and prevention
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles
Monitoring Ligand-Induced Protein Ordering in Drug Discovery
Screening and Development of New Inhibitors of FtsZ from M. Tuberculosis
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of <i>Plasmodium</i>
Pemetrexed and Gemcitabine as Combination Therapy for the Treatment of Group3 Medulloblastoma
Pharmacokinetics and Efficacy of the Spleen Tyrosine Kinase Inhibitor R406 after Ocular Delivery for Retinoblastoma
Treatment of Murine Cerebral Malaria by Artemisone in Combination with Conventional Antimalarial Drugs: Antiplasmodial Effects and Immune Responses
On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53