Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Epigenetics and DNA Methylation, Metabolism, Diabetes, and Cancer, and Metabolomics and Mass Spectrometry Studies.
A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells
Embracing cancer complexity: Hallmarks of systemic disease
Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function
Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2
Regulation of urea cycle by reversible high-stoichiometry lysine succinylation
l-2-Hydroxyglutarate remodeling of the epigenome and epitranscriptome creates a metabolic vulnerability in kidney cancer models
Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
Metabolic adaptation to tyrosine kinase inhibition in leukemia stem cells
Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila
Author Correction: Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila
Metabolomics in cancer research and emerging applications in clinical oncology
PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart
Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification
The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancer
Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers
Metabolic decisions in development and disease—a Keystone Symposia report
Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing
SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease
Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney
T cell stemness and dysfunction in tumors are triggered by a common mechanism
Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism
A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity
SPHK1 Is a Novel Target of Metformin in Ovarian Cancer
Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells
Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis
p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis
Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells
Glutamine Metabolism in Cancer: Understanding the Heterogeneity