Area of research
Molecular Biology · Pharmacology
Research interest
Research interests include Cell biology, Pharmacokinetics, Irinotecan, Neomycin, Hair cell, and Diarrhea.
Gut UGT activity loss precedes the development of irinotecan-induced severe diarrhea: Mechanisms, biomaker and prevention
Optimized rat models better mimic patients with irinotecan-induced severe diarrhea
Hippo/YAP signaling pathway protects against neomycin-induced hair cell damage in the mouse cochlea
Graphene Substrates Promote the Differentiation of Inner Ear Lgr5+ Progenitor Cells Into Hair Cells
Disruption of the autism-related gene Pak1 causes stereocilia disorganization, hair cell loss, and deafness in mice
Blebbistatin Inhibits Neomycin-Induced Apoptosis in Hair Cell-Like HEI-OC-1 Cells and in Cochlear Hair Cells
Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage
Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt
The Roles of Exosomes in Visual and Auditory Systems
Inner Ear Hair Cell Protection in Mammals against the Noise-Induced Cochlear Damage
Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan’s Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea
Glucuronidation: driving factors and their impact on glucuronide disposition
Significantly Decreased and More Variable Expression of Major CYPs and UGTs in Liver Microsomes Prepared from HBV-Positive Human Hepatocellular Carcinoma and Matched Pericarcinomatous Tissues Determined Using an Isotope Label-free UPLC-MS/MS Method
Validation of IMP Dehydrogenase Inhibitors in a Mouse Model of Cryptosporidiosis