Area of research
Molecular Biology · Epidemiology
Research interest
Research interests include Biology, Fibrosis, Inflammation, Medicine, Translational regulation, and Cardiomyopathy.
The cellular and molecular cardiac tissue responses in human inflammatory cardiomyopathies after SARS-CoV-2 infection and COVID-19 vaccination
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies
A high-resolution map of human RNA translation
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury
IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts
Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts
IL‐11 in cardiac and renal fibrosis: Late to the party but a central player
Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease
The Translational Landscape of the Human Heart
Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis
Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function
Titin-truncating variants affect heart function in disease cohorts and the general population
Translational regulation shapes the molecular landscape of complex disease phenotypes
Genomic landscape of rat strain and substrain variation