Area of research
Materials Chemistry · Molecular Biology
Research interest
Research interests include Biology, Cell biology, Cancer research, Ubiquitin, Epigenetics, and Gene.
Age-related noncanonical TRMT6–TRMT61A signaling impairs hematopoietic stem cells
Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence
HER2 phosphorylation induced by TGF-β promotes mammary morphogenesis and breast cancer progression
Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance
Oxidized galectin-1 in SLE fails to bind the inhibitory receptor VSTM1 and increases reactive oxygen species levels in neutrophils
Comprehensive maturity of nuclear pore complexes regulates zygotic genome activation
RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP2
Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals
Methylation of dual-specificity phosphatase 4 controls cell differentiation
Structural basis for zinc-induced activation of a zinc uptake transcriptional regulator
Overexpression of 15-Hydroxyprostaglandin Dehydrogenase Inhibits A549 Lung Adenocarcinoma Cell Growth via Inducing Cell Cycle Arrest and Inhibiting Epithelial-Mesenchymal Transition
Enhancing KDM5A and TLR activity improves the response to immune checkpoint blockade
An E1‐Catalyzed Chemoenzymatic Strategy to Isopeptide‐<i>N</i>‐Ethylated Deubiquitylase‐Resistant Ubiquitin Probes
The 60‐kDa heat shock protein regulates energy rearrangement and protein synthesis to promote proliferation of multiple myeloma cells
A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion
HtrA‐mediated selective degradation of DNA uptake apparatus accelerates termination of pneumococcal transformation
The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery
Cotton Leaf Curl Multan virus C4 protein suppresses both transcriptional and post-transcriptional gene silencing by interacting with SAM synthetase
ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds
HDAC6-mediated acetylation of lipid droplet–binding protein CIDEC regulates fat-induced lipid storage
Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein and has multiple functions
Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing
Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming
Rab8a-AS160-MSS4 Regulatory Circuit Controls Lipid Droplet Fusion and Growth
c-Cbl-Mediated Neddylation Antagonizes Ubiquitination and Degradation of the TGF-β Type II Receptor
Profiling Genome-Wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells
Nonsteroidal anti-inflammatory drug sensitizes <i>Mycobacterium tuberculosis</i> to endogenous and exogenous antimicrobials