Area of research
Molecular Biology · Organic Chemistry
Research interest
Research interests include Glycosylation and Glycoproteins Research, Carbohydrate Chemistry and Synthesis, Monoclonal and Polyclonal Antibodies Research, and Galectins and Cancer Biology.
Apoptotic signaling by TNFR1 is inhibited by the α2-6 sialylation, but not α2-3 sialylation, of the TNFR1 N-glycans
Identification of global inhibitors of cellular glycosylation
H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic
Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions
Role of N-Glycosylation in FcγRIIIa interaction with IgG
Probing the binding specificities of human Siglecs by cell-based glycan arrays
Display of the human mucinome with defined O-glycans by gene engineered cells
Golgi maturation‐dependent glycoenzyme recycling controls glycosphingolipid biosynthesis and cell growth via GOLPH3
Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates
Global view of human protein glycosylation pathways and functions
Glycoengineering of NK Cells with Glycan Ligands of CD22 and Selectins for B‐Cell Lymphoma Therapy
ER-resident oxidoreductases are glycosylated and trafficked to the cell surface to promote matrix degradation by tumour cells
Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides
An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells
Glyco-DIA: a method for quantitative O-glycoproteomics with in silico-boosted glycopeptide libraries
The GAGOme: a cell-based library of displayed glycosaminoglycans
Direct quality control of glycoengineered erythropoietin variants
Targeted Analysis of Lysosomal Directed Proteins and Their Sites of Mannose-6-phosphate Modification
Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins
Mammalian O-mannosylation of cadherins and plexins is independent of protein O-mannosyltransferases 1 and 2
Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma
Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents
Mucins and associated glycan signatures in colon adenoma–carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer
Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions
The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL
A stratigraphic framework for abrupt climatic changes during the Last Glacial period based on three synchronized Greenland ice-core records: refining and extending the INTIMATE event stratigraphy
Consistently dated records from the Greenland GRIP, GISP2 and NGRIP ice cores for the past 104 ka reveal regional millennial-scale δ18O gradients with possible Heinrich event imprint
Precision mapping of the human O‐GalNAc glycoproteome through SimpleCell technology
A first chronology for the North Greenland Eemian Ice Drilling (NEEM) ice core
Initiation of GalNAc-type O-glycosylation in the endoplasmic reticulum promotes cancer cell invasiveness