Area of research
Aging · Molecular Biology
Research interest
Research interests include Genetics, Aging, and Longevity in Model Organisms, Mitochondrial Function and Pathology, Endoplasmic Reticulum Stress and Disease, and Autophagy in Disease and Therapy.
Cross-Organ Mitochondrial Communication in Stress and Disease
The extracellular matrix integrates mitochondrial homeostasis
The germline coordinates mitokine signaling
Cell non-autonomous control of autophagy and metabolism by glial cells
CRISPR screens and lectin microarrays identify high mannose N-glycan regulators
Glial-derived mitochondrial signals affect neuronal proteostasis and aging
The germline coordinates mitokine signaling
The UPRmt preserves mitochondrial import to extend lifespan
Glia of <i>C. elegans</i> coordinate a protective organismal heat shock response independent of the neuronal thermosensory circuit
Four glial cells regulate ER stress resistance and longevity via neuropeptide signaling in <i>C. elegans</i>
UPR <sup>ER</sup> promotes lipophagy independent of chaperones to extend life span
Divergent Nodes of Non-autonomous UPRER Signaling through Serotonergic and Dopaminergic Neurons
Lysosomal recycling of amino acids affects ER quality control
The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER
Spatial regulation of the actin cytoskeleton by HSF-1 during aging
Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity
Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis
Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response