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John Sembrat

University of Pittsburgh · US
Area of research
Pulmonary and Respiratory Medicine · Oncology
Research interest
Research interests include Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, Cancer Immunotherapy and Biomarkers, Pulmonary Hypertension Research and Treatments, and Neonatal Respiratory Health Research.
h-index
34
citations
5,292
works
225
NIH funding
primary concept
email

Recent publications

A deep generative model for deciphering cellular dynamics and in silico drug discovery in complex diseases
Nature Biomedical Engineering 2025cited by 16position: middledoi
Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension
Cellular and Molecular Immunology 2021cited by 86position: middledoi
Frataxin deficiency promotes endothelial senescence in pulmonary hypertension
Journal of Clinical Investigation 2021cited by 74position: middledoi
Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis
European Respiratory Journal 2019cited by 813position: middledoi
Single-cell analysis reveals fibroblast heterogeneity and myofibroblasts in systemic sclerosis-associated interstitial lung disease
Annals of the Rheumatic Diseases 2019cited by 357position: middledoi
Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis
American Journal of Respiratory and Critical Care Medicine 2019cited by 113position: middledoi
BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension
Circulation 2019cited by 78position: middledoi
MicroRNA-144-3p targets relaxin/insulin-like family peptide receptor 1 (RXFP1) expression in lung fibroblasts from patients with idiopathic pulmonary fibrosis
Journal of Biological Chemistry 2019cited by 48position: middledoi
IPF lung fibroblasts have a senescent phenotype
American Journal of Physiology-Lung Cellular and Molecular Physiology 2017cited by 327position: middledoi
Targeting Pulmonary Endothelial Hemoglobin α Improves Nitric Oxide Signaling and Reverses Pulmonary Artery Endothelial Dysfunction
American Journal of Respiratory Cell and Molecular Biology 2017cited by 29position: middledoi
Functional effects of the TMEM43 Ser358Leu mutation in the pathogenesis of arrhythmogenic right ventricular cardiomyopathy
BMC Medical Genetics 2012cited by 21position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Mauricio Rojas · Georgia Institute of Technology4 papers (2017–2021)Ana L. Mora · The Ohio State University Wexner Medical Center3 papers (2017–2019)Humberto E. Trejo Bittar · Moffitt Cancer Center2 papers (2019–2019)Mauricio Rojas · Lung Institute2 papers (2017–2019)Tracy Tabib · University of Pittsburgh2 papers (2019–2019)Robert Lafyatis · La Roche College2 papers (2019–2019)Eleanor Valenzi · University of Pittsburgh2 papers (2019–2019)Diana Álvarez · Institute of Aging2 papers (2017–2019)Christina Morse · University of Pittsburgh2 papers (2019–2019)Daniel J. Kass · University of Pittsburgh2 papers (2019–2019)Taylor Adams · Yale University1 papers (2025–2025)Mehdi Nouraie · University of Pittsburgh1 papers (2017–2017)Hannah D’Cunha · Creighton University1 papers (2017–2017)Partha Dutta · University of Pittsburgh1 papers (2021–2021)Chandler Caufield · University of Pittsburgh1 papers (2017–2017)Jun Ding · McGill University Health Centre1 papers (2025–2025)Yi‐Yin Tai · Sun Yat-sen University1 papers (2021–2021)Kristina L. Buschur · Columbia University Irving Medical Center1 papers (2019–2019)Marie Vermant · KU Leuven1 papers (2025–2025)Melissa Bulik · University of Pittsburgh1 papers (2019–2019)