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Helen Skaletsky

Howard Hughes Medical Institute · US
Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities, Chromosomal and Genetic Variations, Genomics and Chromatin Dynamics, and Animal Genetics and Reproduction.
h-index
37
citations
26,589
works
91
NIH funding
primary concept
email

Recent publications

Genes of the Fatty Acid Oxidation Pathway are Upregulated in Female as Compared to Male Cardiomyocytes
Circulation 2025cited by 2position: middledoi
Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal and Xa responses in vivo and in vitro in four human cell types
Cell Genomics 2024cited by 16position: middledoi
The human inactive X chromosome modulates expression of the active X chromosome
Cell Genomics 2023cited by 85position: middledoi
The human Y and inactive X chromosomes similarly modulate autosomal gene expression
Cell Genomics 2023cited by 50position: middledoi
A gene deriving from the ancestral sex chromosomes was lost from the X and retained on the Y chromosome in eutherian mammals
BMC Biology 2022cited by 10position: middledoi
Genetic characterization of a missense mutation in the X-linked <i>TAF7L</i> gene identified in an oligozoospermic man
Biology of Reproduction 2022cited by 6position: middledoi
SHIMS 3.0: Highly efficient single-haplotype iterative mapping and sequencing using ultra-long nanopore reads
PLoS ONE 2022cited by 2position: middledoi
GC-biased gene conversion in X-chromosome palindromes conserved in human, chimpanzee, and rhesus macaque
G3 Genes Genomes Genetics 2021cited by 6position: middledoi
Selection Has Countered High Mutability to Preserve the Ancestral Copy Number of Y Chromosome Amplicons in Diverse Human Lineages
The American Journal of Human Genetics 2018cited by 42position: middledoi
Cost-effective high-throughput single-haplotype iterative mapping and sequencing for complex genomic structures
Nature Protocols 2018cited by 20position: middledoi
Avian W and mammalian Y chromosomes convergently retained dosage-sensitive regulators
Nature Genetics 2017cited by 190position: middledoi
Intrinsic fertility of human oocytes
Fertility and Sterility 2017cited by 76position: middledoi
Avian W and mammalian Y chromosomes convergently retained dosage-sensitive regulators
PMC 2017cited by 4position: middle
Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining
Nature Cell Biology 2016cited by 285position: middledoi
A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes
eLife 2016cited by 71position: middledoi
TEX11 is mutated in infertile men with azoospermia and regulates genome‐wide recombination rates in mouse
EMBO Molecular Medicine 2015cited by 190position: middledoi
Sex chromosome-to-autosome transposition events counter Y-chromosome gene loss in mammals
Genome Biology 2015cited by 96position: middledoi
Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators
Nature 2014cited by 667position: middledoi
Sequencing the Mouse Y Chromosome Reveals Convergent Gene Acquisition and Amplification on Both Sex Chromosomes
Cell 2014cited by 355position: middledoi
Intrachromosomal homologous recombination between inverted amplicons on opposing Y-chromosome arms
Genomics 2013cited by 25position: middledoi
Independent specialization of the human and mouse X chromosomes for the male germ line
Nature Genetics 2013cited by 7position: middledoi
Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes
Nature 2012cited by 306position: middledoi
Sequencing of rhesus macaque Y chromosome clarifies origins and evolution of the <i>DAZ</i> (<i>Deleted in AZoospermia</i>) genes
BioEssays 2012cited by 22position: middledoi
AZFc Deletions and Spermatogenic Failure: A Population-Based Survey of 20,000 Y Chromosomes
The American Journal of Human Genetics 2012cited by 7position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

David C. Page · Howard Hughes Medical Institute20 papers (2012–2025)Jennifer F. Hughes · Whitehead Institute for Biomedical Research8 papers (2012–2024)Daniel W. Bellott · Whitehead Institute for Biomedical Research8 papers (2016–2023)Tatyana Pyntikova · Whitehead Institute for Biomedical Research6 papers (2014–2022)Laura Brown · Birmingham Community Healthcare NHS Trust6 papers (2012–2024)Natalia Koutseva · Whitehead Institute for Biomedical Research4 papers (2014–2017)Tina Graves · Washington University in St. Louis4 papers (2013–2017)Richard K. Wilson · Nationwide Children's Hospital4 papers (2013–2017)Sherman J. Silber · Saint Louis University4 papers (2012–2022)Wesley C. Warren · Florida Atlantic University4 papers (2013–2017)Laura G. Brown · Centers for Disease Control and Prevention3 papers (2013–2023)Steve Rozen · Chang Gung University3 papers (2012–2015)David C. Page · Abbott (United Kingdom)3 papers (2014–2017)Ting-Jan Cho · Whitehead Institute for Biomedical Research3 papers (2017–2022) · 3 papers (2014–2017)Robert D. Oates · Boston University3 papers (2012–2022)P. Jeremy Wang · China Pharmaceutical University2 papers (2015–2022)Maximilian Muenke · Australian National University2 papers (2023–2024)Paul Kruszka · National Human Genome Research Institute2 papers (2023–2024)Levi S. Teitz · Massachusetts Institute of Technology2 papers (2016–2018)