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Jennifer F. Hughes

Whitehead Institute for Biomedical Research · US
Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities, Chromosomal and Genetic Variations, Genomics and Chromatin Dynamics, and Animal Genetics and Reproduction.
h-index
20
citations
4,021
works
58
NIH funding
primary concept
email

Recent publications

Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal and Xa responses in vivo and in vitro in four human cell types
Cell Genomics 2024cited by 16position: middledoi
The human inactive X chromosome modulates expression of the active X chromosome
Cell Genomics 2023cited by 85position: middledoi
Human microglia maturation is underpinned by specific gene regulatory networks
Immunity 2023cited by 60position: middledoi
The human Y and inactive X chromosomes similarly modulate autosomal gene expression
Cell Genomics 2023cited by 50position: middledoi
A gene deriving from the ancestral sex chromosomes was lost from the X and retained on the Y chromosome in eutherian mammals
BMC Biology 2022cited by 10position: firstdoi
SHIMS 3.0: Highly efficient single-haplotype iterative mapping and sequencing using ultra-long nanopore reads
PLoS ONE 2022cited by 2position: middledoi
Conservation, acquisition, and functional impact of sex-biased gene expression in mammals
Science 2019cited by 291position: middledoi
Cost-effective high-throughput single-haplotype iterative mapping and sequencing for complex genomic structures
Nature Protocols 2018cited by 20position: middledoi
The history of the Y chromosome in man
Nature Genetics 2016cited by 17position: firstdoi
The Biology and Evolution of Mammalian Y Chromosomes
Annual Review of Genetics 2015cited by 164position: firstdoi
Sex chromosome-to-autosome transposition events counter Y-chromosome gene loss in mammals
Genome Biology 2015cited by 96position: firstdoi
Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators
Nature 2014cited by 667position: middledoi
Sequencing the Mouse Y Chromosome Reveals Convergent Gene Acquisition and Amplification on Both Sex Chromosomes
Cell 2014cited by 355position: middledoi
Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes
Nature 2012cited by 306position: firstdoi
Genomics and Genetics of Human and Primate Y Chromosomes
Annual Review of Genomics and Human Genetics 2012cited by 103position: firstdoi
Sequencing of rhesus macaque Y chromosome clarifies origins and evolution of the <i>DAZ</i> (<i>Deleted in AZoospermia</i>) genes
BioEssays 2012cited by 22position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

David C. Page · Howard Hughes Medical Institute11 papers (2012–2024)Helen Skaletsky · Howard Hughes Medical Institute8 papers (2012–2024)Daniel W. Bellott · Whitehead Institute for Biomedical Research4 papers (2018–2023)Alexander K. Godfrey · Massachusetts Institute of Technology3 papers (2019–2024)Tatyana Pyntikova · Whitehead Institute for Biomedical Research3 papers (2014–2022)Ting-Jan Cho · Whitehead Institute for Biomedical Research2 papers (2018–2022)Ashley Buscetta · National Heart Lung and Blood Institute2 papers (2023–2024) · 2 papers (2023–2024) · 2 papers (2023–2024)Nicole Banks · Virginia Commonwealth University2 papers (2023–2024)Maximilian Muenke · Australian National University2 papers (2023–2024)Steve Rozen · Chang Gung University2 papers (2012–2014)Natalia Koutseva · Whitehead Institute for Biomedical Research2 papers (2014–2015)Paul Kruszka · National Human Genome Research Institute2 papers (2023–2024)Laura Brown · Birmingham Community Healthcare NHS Trust2 papers (2014–2024)Angela E. Lin · Massachusetts General Hospital1 papers (2024–2024)Patrick Minx · Retina Institute1 papers (2014–2014)Richard K. Wilson · Nationwide Children's Hospital1 papers (2014–2014)Shanlee Davis · University of Colorado Denver1 papers (2023–2023)Jessica Alföldi · Broad Institute1 papers (2014–2014)