Area of research
Cell Biology · Molecular Biology
Research interest
Research interests include Biology, Cell biology, Kinetochore, Mitosis, Microtubule, and Centromere.
Global stabilization of the transcriptome in mitotic cells
Nuclear release of eIF1 restricts start-codon selection during mitosis
Alternative CDC20 translational isoforms tune mitotic arrest duration
The phenotypic landscape of essential human genes
Kinetochore assembly throughout the cell cycle
Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition
Cellular Mechanisms and Regulation of Quiescence
Alpha-satellite RNA transcripts are repressed by centromere–nucleolus associations
Cohesin Removal Reprograms Gene Expression upon Mitotic Entry
Quiescent Cells Actively Replenish CENP-A Nucleosomes to Maintain Centromere Identity and Proliferative Potential
Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion
The kinetochore–microtubule interface at a glance
Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype
Large-Scale Analysis of CRISPR/Cas9 Cell-Cycle Knockouts Reveals the Diversity of p53-Dependent Responses to Cell-Cycle Defects
Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition
A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends
The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface
Inferring transient particle transport dynamics in live cells
Chromosome Segregation: A Spatial Code to Correct Kinetochore–Microtubule Attachments
Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program
The outer kinetochore protein KNL-1 contains a defined oligomerization domain in nematodes
Cortical Dynein and Asymmetric Membrane Elongation Coordinately Position the Spindle in Anaphase
CENP‐T provides a structural platform for outer kinetochore assembly
CDK-dependent phosphorylation and nuclear exclusion coordinately control kinetochore assembly state
Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis
Induced dicentric chromosome formation promotes genomic rearrangements and tumorigenesis
The functions and consequences of force at kinetochores
Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant
CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like Fold
The Kinetochore-Bound Ska1 Complex Tracks Depolymerizing Microtubules and Binds to Curved Protofilaments