Area of research
Infectious Diseases · Molecular Biology
Research interest
Research interests include Chemistry, Virology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Protease, Proteases, and Aptamer.
Bioinspired designer DNA NanoGripper for virus sensing and potential inhibition
Polyvalent Nanobody Structure Designed for Boosting SARS-CoV-2 Inhibition
An orally active entry inhibitor of influenza A viruses protects mice and synergizes with oseltamivir and baloxavir marboxil
Non-Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity
Evolution of SARS-CoV-2 in the murine central nervous system drives viral diversification
N-Substituted Pyrrole-Based Heterocycles as Broad-Spectrum Filoviral Entry Inhibitors
Suppression of interferon α and γ response by Huwe1-mediated Miz1 degradation promotes SARS-CoV-2 replication
Sulforaphane is a reversible covalent inhibitor of 3‐chymotrypsin‐like protease of SARS‐CoV‐2
Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants
Inter-domain communication in SARS-CoV-2 spike proteins controls protease-triggered cell entry
An ACE2 decoy can be administered by inhalation and potently targets omicron variants of SARS‐CoV‐2
Synthesis, Optimization, and Structure–Activity Relationships of Imidazo[1,2-<i>a</i>]pyrimidines as Inhibitors of Group 2 Influenza A Viruses
Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity
Direct detection of human adenovirus or SARS-CoV-2 with ability to inform infectivity using DNA aptamer-nanopore sensors
Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases
Discovery of chebulagic acid and punicalagin as novel allosteric inhibitors of SARS-CoV-2 3CLpro
Targeting SARS‐CoV‐2 viral proteases as a therapeutic strategy to treat COVID‐19
ACE2-IgG1 fusions with improved in vitro and in vivo activity against SARS-CoV-2
Label-Free Digital Detection of Intact Virions by Enhanced Scattering Microscopy
Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry
A recombinant Cedar virus based high-throughput screening assay for henipavirus antiviral discovery
Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors
LAYN Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric and Colon Cancers