Area of research
Infectious Diseases · Animal Science and Zoology
Research interest
Research interests include Virology, Coronavirus, Antibody, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Coronavirus disease 2019 (COVID-19), and Biology.
SARS-CoV-2 spike protein: a key target for eliciting persistent neutralizing antibodies
Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion
Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses
Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China
An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies
Learning from the past: development of safe and effective COVID-19 vaccines
Neutralizing antibodies for the treatment of COVID-19
Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2
Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with aluminum hydroxide induces protective immunity and reduces immune enhancement
Therapeutic antibodies and fusion inhibitors targeting the spike protein of SARS-CoV-2
Current development of COVID-19 diagnostics, vaccines and therapeutics
From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development
Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen
Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III
Vaccines for the prevention against the threat of MERS-CoV
Cell Entry of Porcine Epidemic Diarrhea Coronavirus Is Activated by Lysosomal Proteases
Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus
Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection
Optimization of antigen dose for a receptor-binding domain-based subunit vaccine against MERS coronavirus
Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease
Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines
Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments—The importance of immunofocusing in subunit vaccine design
Advancements in the development of subunit influenza vaccines
Receptor-binding domain-based subunit vaccines against MERS-CoV
Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development
A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines
Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate
Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome
A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC