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Lanying Du

Shanghai Medical College of Fudan University · CN
Area of research
Infectious Diseases · Animal Science and Zoology
Research interest
Research interests include Virology, Coronavirus, Antibody, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Coronavirus disease 2019 (COVID-19), and Biology.
h-index
citations
7,507
works
30
NIH funding
primary concept
email

Recent publications

SARS-CoV-2 spike protein: a key target for eliciting persistent neutralizing antibodies
Signal Transduction and Targeted Therapy 2021cited by 132position: lastdoi
Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine
Cellular and Molecular Immunology 2020cited by 1,813position: lastdoi
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion
Cell Research 2020cited by 1,432position: middledoi
Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses
Trends in Immunology 2020cited by 935position: lastdoi
Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China
Microbes and Infection 2020cited by 375position: middledoi
An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies
Emerging Microbes & Infections 2020cited by 351position: middledoi
Learning from the past: development of safe and effective COVID-19 vaccines
Nature Reviews Microbiology 2020cited by 175position: middledoi
Neutralizing antibodies for the treatment of COVID-19
Nature Biomedical Engineering 2020cited by 133position: lastdoi
Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2
Antiviral Research 2020cited by 127position: lastdoi
Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with aluminum hydroxide induces protective immunity and reduces immune enhancement
Vaccine 2020cited by 108position: middledoi
Therapeutic antibodies and fusion inhibitors targeting the spike protein of SARS-CoV-2
Expert Opinion on Therapeutic Targets 2020cited by 65position: lastdoi
Current development of COVID-19 diagnostics, vaccines and therapeutics
Microbes and Infection 2020cited by 56position: middledoi
From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development
Microbes and Infection 2020cited by 54position: middledoi
Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen
Vaccine 2018cited by 71position: middledoi
Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III
Emerging Microbes & Infections 2017cited by 51position: middledoi
Vaccines for the prevention against the threat of MERS-CoV
Expert Review of Vaccines 2016cited by 104position: firstdoi
Cell Entry of Porcine Epidemic Diarrhea Coronavirus Is Activated by Lysosomal Proteases
Journal of Biological Chemistry 2016cited by 58position: middledoi
Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus
Journal of Virology 2015cited by 144position: middledoi
Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection
The Journal of Infectious Diseases 2015cited by 102position: middledoi
Optimization of antigen dose for a receptor-binding domain-based subunit vaccine against MERS coronavirus
Human Vaccines & Immunotherapeutics 2015cited by 80position: middledoi
Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease
Journal of Virology 2015cited by 80position: middledoi
Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines
Vaccine 2014cited by 144position: middledoi
Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments—The importance of immunofocusing in subunit vaccine design
Vaccine 2014cited by 135position: lastdoi
Advancements in the development of subunit influenza vaccines
Microbes and Infection 2014cited by 63position: lastdoi
Receptor-binding domain-based subunit vaccines against MERS-CoV
Virus Research 2014cited by 62position: lastdoi
Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development
Journal of Virology 2013cited by 182position: firstdoi
A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines
PLoS ONE 2013cited by 164position: firstdoi
Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate
Human Vaccines & Immunotherapeutics 2013cited by 129position: middledoi
Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome
Expert Review of Vaccines 2012cited by 140position: middledoi
A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC
Journal of Infection 2012cited by 42position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Shibo Jiang · Shanghai Medical College of Fudan University29 papers (2012–2020)Chien‐Te K. Tseng · Galveston College9 papers (2012–2020)Yusen Zhou · Southeast University9 papers (2013–2020)Lu Lu · University of Science and Technology8 papers (2012–2020)Xinrong Tao · Anhui Medical University7 papers (2013–2020)Cuiqing Ma · Hebei Medical University6 papers (2013–2020)Peter J. Hotez · Professional Beef Services5 papers (2012–2020)Yang Yang · University of Science and Technology of China5 papers (2014–2021)Naru Zhang · Zhejiang University5 papers (2014–2020)Wanbo Tai · Tsinghua University5 papers (2016–2020)Xiujuan Zhang · Fudan University4 papers (2020–2020)María Elena Bottazzi · Baylor University4 papers (2012–2020)Guangyu Zhao · Shenyang Ligong University4 papers (2013–2015)Anurodh Shankar Agrawal · The University of Texas Medical Branch at Galveston3 papers (2015–2020)Fang Li · University of Minnesota3 papers (2014–2016)Abdullah Algaissi · The University of Texas Medical Branch at Galveston3 papers (2015–2020) · 3 papers (2012–2020)Bi-Hung Peng · The University of Texas Medical Branch at Galveston3 papers (2015–2020)Shuai Xia · Shanghai Medical College of Fudan University2 papers (2015–2020)Lili Wang · Hebei Agricultural University2 papers (2014–2020)