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Lu Lu

University of Science and Technology ·
Area of research
Infectious Diseases · Virology
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, HIV Research and Treatment, HIV/AIDS drug development and treatment, and COVID-19 Clinical Research Studies.
h-index
65
citations
21,251
works
455
NIH funding
primary concept
email

Recent publications

STING agonist-based ER-targeting molecules boost antigen cross-presentation
Nature 2025cited by 53position: middledoi
Prognostic and diagnostic value of [18F]FDG, 11C-acetate, and [68Ga]Ga-FAPI-04 PET/CT for hepatocellular carcinoma
European Radiology 2025cited by 8position: middledoi
Development and mechanistic investigation of recombinant type III humanized collagen gel for mid-facial soft tissue repair
Collagen and Leather 2025cited by 4position: middledoi
Yuzhuo Zhixiao pill can treat non-alcoholic steatohepatitis through modulation of gut microbiota, bile acid and short-chain fatty acid metabolism
Phytomedicine 2025cited by 3position: middledoi
Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma
Cell Reports Medicine 2024cited by 64position: middledoi
Integrating Single-Cell and Spatial Transcriptomics to Uncover and Elucidate GP73-Mediated Pro-Angiogenic Regulatory Networks in Hepatocellular Carcinoma
Research 2024cited by 44position: middledoi
Targeting SPP1-orchestrated neutrophil extracellular traps-dominant pre-metastatic niche reduced HCC lung metastasis
Experimental Hematology and Oncology 2024cited by 26position: middledoi
QL1706 (anti-PD-1 IgG4/CTLA-4 antibody) plus chemotherapy with or without bevacizumab in advanced non-small cell lung cancer: a multi-cohort, phase II study
Signal Transduction and Targeted Therapy 2024cited by 19position: middledoi
Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein
Nature Communications 2024cited by 19position: middledoi
Stigmasterol mitigates estrogen-deficiency-induced osteoporosis through inhibition of phosphorylated p65 and MAPK signaling pathways
Frontiers in Pharmacology 2024cited by 4position: middledoi
Langerhans cell histiocytosis mimicking hematoma of the lower eyelid: A case report
Medicine 2024cited by 0position: middledoi
An engineered recombinant protein containing three structural domains in SARS-CoV-2 S2 protein has potential to act as a pan-human coronavirus entry inhibitor or vaccine antigen
Emerging Microbes & Infections 2023cited by 23position: middledoi
Characteristic analysis of intraocular hypertension in patients with high myopia after vitrectomy combined with silicone oil tamponade
Research Square 2023cited by 0position: middledoi
Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody
Cell 2022cited by 180position: middledoi
Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages
Signal Transduction and Targeted Therapy 2022cited by 176position: middledoi
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2
Nature Microbiology 2022cited by 151position: middledoi
The combination of PD-1 blockade with interferon-α has a synergistic effect on hepatocellular carcinoma
Cellular and Molecular Immunology 2022cited by 138position: middledoi
Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant
Cell Research 2022cited by 40position: middledoi
Predicting unseen antibodies’ neutralizability via adaptive graph neural networks
Nature Machine Intelligence 2022cited by 36position: middledoi
Sertraline Is an Effective SARS-CoV-2 Entry Inhibitor Targeting the Spike Protein
Journal of Virology 2022cited by 28position: middledoi
AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells
Cell Research 2021cited by 507position: middledoi
Antivirals with common targets against highly pathogenic viruses
Cell 2021cited by 159position: firstdoi
68Ga-FAPI-04 Versus 18F-FDG PET/CT in the Detection of Hepatocellular Carcinoma
Frontiers in Oncology 2021cited by 114position: middledoi
Characteristics of pre-metastatic niche: the landscape of molecular and cellular pathways
Molecular Biomedicine 2021cited by 77position: middledoi
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation
Signal Transduction and Targeted Therapy 2021cited by 68position: lastdoi
A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants
Signal Transduction and Targeted Therapy 2021cited by 39position: middledoi
The impact of receptor-binding domain natural mutations on antibody recognition of SARS-CoV-2
Signal Transduction and Targeted Therapy 2021cited by 38position: middledoi
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion
Cell Research 2020cited by 1,432position: lastdoi
Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
Emerging Microbes & Infections 2020cited by 1,274position: middledoi
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
Cellular and Molecular Immunology 2020cited by 755position: lastdoi

Grants

OAC Core: Revolutionizing Data Movement on DPU-Powered HPC and AI Cyberinfrastructures
NSF2623610$596,7382026–2028PIRePORTER
CAREER: Mechanistically Informed Modeling of 3D Urban Morphology and Real-Time Exposure to PM2.5
NSF2540973$585,4972026–2031PIRePORTER
CAREER: Heterogeneity-Enriched Communication for Advancing HPC Systems and Applications
NSF2623548$482,1932026–2028PIRePORTER
REU Site: Integrative Cell and Molecular Biology
NSF2548189$416,0252026–2029PIRePORTER
REU Site: Dare to BE FIRST - Biomechanical Engineering Foundations in Impactful Research, Science & Technology
NSF2548398$414,8582026–2029PIRePORTER
Collaborative Research: DMS/NIGSM 1: Statistical methods for estimating direct genetic effect
NSF2553818$300,0002026–2029PIRePORTER
CyberTraining: Pilot: Cross-Layer Training of High-Performance Deep Learning Technologies and Applications for Research Workforce Development in Central Valley
NSF2623546$176,9652026–2026PIRePORTER
Collaborative Research: EAGER: Automating CI Configuration Troubleshooting with Bayesian Group Testing
NSF2623611$58,5302026–2026PIRePORTER
Collaborative Research: Framework: QUACS - Quick Updates to Aerosol and Chemistry Systems for Next Generation Multi-Scale Models
NSF2513282$740,5152025–2030PIRePORTER
Advancing Adaptive Optics into the Visible for Black Hole Science
NSF2511697$678,2442025–2028PIRePORTER
OAC Core: Cyberinfrastructure for Multi-Stream Architectures Applied to Computer Vision: Efficiency via Co-Design of Network Architectures and Framework Operators
NSF2504445$660,0002025–2028PIRePORTER
OAC Core: Revolutionizing Data Movement on DPU-Powered HPC and AI Cyberinfrastructures
NSF2505106$596,7382025–2026PIRePORTER
PFI (MCA): Developing Safe and Affordable Alternatives to Horseshoe Crab Blood for Detecting Harmful Bacterial Toxins
NSF2423223$337,6322025–2028PIRePORTER
Collaborative Research: Well-Designed Nanofiber-Encapsulated Bimetallic Catalysts for CO2 Conversion: Addressing Catalyst Deactivation Challenges
NSF2553809$314,8802025–2028PIRePORTER
Collaborative Research: Well-Designed Nanofiber-Encapsulated Bimetallic Catalysts for CO2 Conversion: Addressing Catalyst Deactivation Challenges
NSF2452326$314,8802025–2025PIRePORTER
Collaborative Research: Towards an AI-Empowered Market-Driven Spectrum System with Strategic and Adversarial Users
NSF2433888$308,7502025–2028PIRePORTER
CAREER: Mathematical Foundations of Generative Scientific Deep Learning
NSF2442463$296,0232025–2030PIRePORTER
NSF-BSF: Learning from Ensemble Data: trajectory recovery and flow-map inference for multiple systems
NSF2511283$209,9982025–2028PIRePORTER
Collaborative Research: eMB: A deep learning-enhanced multiphysics and multiscale framework for mechanistic modeling of erythrophagocytosis
NSF2527294$100,0002025–2028PIRePORTER
I-Corps: Translation Potential of a Platform for Battery Design Optimization
NSF2526642$50,0002025–2027PIRePORTER

Frequent collaborators

Shibo Jiang · Shanghai Medical College of Fudan University39 papers (2012–2025)Shuai Xia · Shanghai Medical College of Fudan University20 papers (2015–2023)Wei Xu · Shanghai Medical College of Fudan University17 papers (2017–2023)Tianlei Ying · Shanghai Medical College of Fudan University11 papers (2016–2024)Youhua Xie · Shanghai Medical College of Fudan University10 papers (2020–2022)Yanling Wu · Yanbian University9 papers (2017–2024)Yun Zhu · Nanjing Agricultural University9 papers (2015–2023)Qian Wang · Fudan University8 papers (2016–2022)Lun–Xiu Qin · Fudan University8 papers (2019–2025)Lanying Du · Shanghai Medical College of Fudan University8 papers (2012–2020)Xinling Wang · Fudan University7 papers (2020–2023)Zezhong Liu · Fudan University6 papers (2020–2025)Qiaoshuai Lan · Fudan University6 papers (2020–2022)Xia Cai · Shanghai Medical College of Fudan University5 papers (2020–2021)Qiongzhu Dong · Fudan University5 papers (2019–2024)Yu Kong · Fudan University4 papers (2017–2024)Chenjian Gu · Washington University in St. Louis4 papers (2020–2020)Xiao‐Dong Zhu · Qingdao University of Science and Technology4 papers (2013–2013)Hui‐Chuan Sun · Jiangsu University4 papers (2013–2013)Zhenlin Yang · Fudan University4 papers (2020–2024)