Area of research
Infectious Diseases · Virology
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, HIV Research and Treatment, HIV/AIDS drug development and treatment, and COVID-19 Clinical Research Studies.
STING agonist-based ER-targeting molecules boost antigen cross-presentation
Prognostic and diagnostic value of [18F]FDG, 11C-acetate, and [68Ga]Ga-FAPI-04 PET/CT for hepatocellular carcinoma
Development and mechanistic investigation of recombinant type III humanized collagen gel for mid-facial soft tissue repair
Yuzhuo Zhixiao pill can treat non-alcoholic steatohepatitis through modulation of gut microbiota, bile acid and short-chain fatty acid metabolism
Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma
Integrating Single-Cell and Spatial Transcriptomics to Uncover and Elucidate GP73-Mediated Pro-Angiogenic Regulatory Networks in Hepatocellular Carcinoma
Targeting SPP1-orchestrated neutrophil extracellular traps-dominant pre-metastatic niche reduced HCC lung metastasis
QL1706 (anti-PD-1 IgG4/CTLA-4 antibody) plus chemotherapy with or without bevacizumab in advanced non-small cell lung cancer: a multi-cohort, phase II study
Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein
Stigmasterol mitigates estrogen-deficiency-induced osteoporosis through inhibition of phosphorylated p65 and MAPK signaling pathways
Langerhans cell histiocytosis mimicking hematoma of the lower eyelid: A case report
An engineered recombinant protein containing three structural domains in SARS-CoV-2 S2 protein has potential to act as a pan-human coronavirus entry inhibitor or vaccine antigen
Characteristic analysis of intraocular hypertension in patients with high myopia after vitrectomy combined with silicone oil tamponade
Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody
Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2
The combination of PD-1 blockade with interferon-α has a synergistic effect on hepatocellular carcinoma
Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant
Predicting unseen antibodies’ neutralizability via adaptive graph neural networks
Sertraline Is an Effective SARS-CoV-2 Entry Inhibitor Targeting the Spike Protein
AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells
Antivirals with common targets against highly pathogenic viruses
68Ga-FAPI-04 Versus 18F-FDG PET/CT in the Detection of Hepatocellular Carcinoma
Characteristics of pre-metastatic niche: the landscape of molecular and cellular pathways
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation
A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants
The impact of receptor-binding domain natural mutations on antibody recognition of SARS-CoV-2
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion
Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
OAC Core: Revolutionizing Data Movement on DPU-Powered HPC and AI Cyberinfrastructures
CAREER: Mechanistically Informed Modeling of 3D Urban Morphology and Real-Time Exposure to PM2.5
CAREER: Heterogeneity-Enriched Communication for Advancing HPC Systems and Applications
REU Site: Integrative Cell and Molecular Biology
REU Site: Dare to BE FIRST - Biomechanical Engineering Foundations in Impactful Research, Science & Technology
Collaborative Research: DMS/NIGSM 1: Statistical methods for estimating direct genetic effect
CyberTraining: Pilot: Cross-Layer Training of High-Performance Deep Learning Technologies and Applications for Research Workforce Development in Central Valley
Collaborative Research: EAGER: Automating CI Configuration Troubleshooting with Bayesian Group Testing
Collaborative Research: Framework: QUACS - Quick Updates to Aerosol and Chemistry Systems for Next Generation Multi-Scale Models
Advancing Adaptive Optics into the Visible for Black Hole Science
OAC Core: Cyberinfrastructure for Multi-Stream Architectures Applied to Computer Vision: Efficiency via Co-Design of Network Architectures and Framework Operators
OAC Core: Revolutionizing Data Movement on DPU-Powered HPC and AI Cyberinfrastructures
PFI (MCA): Developing Safe and Affordable Alternatives to Horseshoe Crab Blood for Detecting Harmful Bacterial Toxins
Collaborative Research: Well-Designed Nanofiber-Encapsulated Bimetallic Catalysts for CO2 Conversion: Addressing Catalyst Deactivation Challenges
Collaborative Research: Well-Designed Nanofiber-Encapsulated Bimetallic Catalysts for CO2 Conversion: Addressing Catalyst Deactivation Challenges
Collaborative Research: Towards an AI-Empowered Market-Driven Spectrum System with Strategic and Adversarial Users
CAREER: Mathematical Foundations of Generative Scientific Deep Learning
NSF-BSF: Learning from Ensemble Data: trajectory recovery and flow-map inference for multiple systems
Collaborative Research: eMB: A deep learning-enhanced multiphysics and multiscale framework for mechanistic modeling of erythrophagocytosis
I-Corps: Translation Potential of a Platform for Battery Design Optimization