Area of research
Infectious Diseases · Structural Biology
Research interest
Research focused on Virology and Coronavirus, with related work in Immune system, Spike Protein, Furin. Notable publications include 'Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate...', 'Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein', and 'The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin'.
BTFBS: Binding Prediction of Bacterial Transcription Factors and Binding Sites Based on Deep Learning
Recombinant humanized type I collagen remodels decidual immune microenvironment at maternal-fetal interface by modulating Th17/Treg imbalance
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation
An engineered recombinant protein containing three structural domains in SARS-CoV-2 S2 protein has potential to act as a pan-human coronavirus entry inhibitor or vaccine antigen
Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity
Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages
Cryo-EM structure and electrophysiological characterization of ALMT from <i>Glycine max</i> reveal a previously uncharacterized class of anion channels
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin
An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene
A randomized open-label clinical trial of an anti-HPV biological dressing (JB01-BD) administered intravaginally to treat high-risk HPV infection
Safety evaluation of chemically modified beta‐lactoglobulin administered intravaginally
Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae