Area of research
Infectious Diseases · Oncology
Research interest
Research interests include Monoclonal antibody, Antibody, Epitope, T cell, Virology, and Apoptosis.
Association of blood urea nitrogen with all-cause and cardiovascular mortality in hyperlipidemia: NHANES 1999–2018
Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress
Prophylactic efficacy of an intranasal spray with 2 synergetic antibodies neutralizing Omicron
Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium
An efficient new adaptive variational mode decomposition algorithm for extracting adventitious lung sounds
Identification of cross-reactive CD8+ T cell receptors with high functional avidity to a SARS-CoV-2 immunodominant epitope and its natural mutant variants
IL-21 Optimizes the CAR-T Cell Preparation Through Improving Lentivirus Mediated Transfection Efficiency of T Cells and Enhancing CAR-T Cell Cytotoxic Activities
Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
A Rapid and Efficient Screening System for Neutralizing Antibodies and Its Application for SARS-CoV-2
p38 inhibition enhances TCR-T cell function and antagonizes the immunosuppressive activity of TGF-β
TRAIL-R1-Targeted CAR-T Cells Exhibit Dual Antitumor Efficacy
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
TRAIL-R1-targeted chimeric antigen receptor T cells exhibit dual antitumor effects
A rapid and efficient screening system for neutralizing antibodies and its application for the discovery of potent neutralizing antibodies to SARS-CoV-2 S-RBD
Identification of Cross-Reactive CD8 <sup>+</sup> T Cell Receptors with High Functional Avidity to a SARS-CoV-2 Immunodominant Epitope and Its Natural Mutant Variants
A key linear epitope for a potent neutralizing antibody to SARS-CoV-2 S-RBD
Immune characteristics analysis reveals two key inflammatory factors correlated to the expressions of SARS-CoV-2 S1-specific antibodies
A rapid and efficient screening system for neutralizing antibodies and its application for SARS-CoV-2
Analysis of the clinical significance of DCLK1<sup>+</sup> colorectal cancer using novel monoclonal antibodies against DCLK1
Combination of tumor necrosis factor related apoptosis-inducing ligand with its type-I receptor-specific monoclonal antibody enhanced anti-tumor effects in vitro and in vivo
Amyloid β-42 induces neuronal apoptosis by targeting mitochondria
Identification of Novel Epitopes with Agonistic Activity for the Development of Tumor Immunotherapy Targeting TRAIL-R1
Fully human monoclonal antibodies to TRAIL-R1 enhance TRAIL-induced apoptosis via activation of caspase-8 pathway
Immunotherapy based on chimeric antigen Receptor T cell for solid Cancers
Establishment of a high efficient expression system of a novol human monoclonal antibody against tumour necrosis factor-related apoptosis-inducing ligand receptor and its functional characteristics
Establishment of activation and differentiation of memory B cells into antigen-specific secreting cells from peripheral blood mononuclear cells in vitro