Area of research
Infectious Diseases · Oncology
Research interest
Research focused on Avidity and Cytotoxic T cell, with related work in Monoclonal antibody, Neutralization, Epitope. Notable publications include 'Identification of cross-reactive CD8+ T cell receptors with high functional avidity to a SARS-CoV-2 immunodominant epitope and its natural mutant variants', 'Long Noncoding RNAs Control the Modulation of Immune Checkpoint Molecules in Cancer', and 'IL-21 Optimizes the CAR-T Cell Preparation Through Improving Lentivirus Mediated Transfection Efficiency of T Cells and Enhancing CAR-T Cell Cytotoxic Activities'.
Age heterogeneity in the association between malnutrition and early childhood development among children aged 0–5 years in a Chinese plateau area
Prophylactic efficacy of an intranasal spray with 2 synergetic antibodies neutralizing Omicron
Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium
Identification of cross-reactive CD8+ T cell receptors with high functional avidity to a SARS-CoV-2 immunodominant epitope and its natural mutant variants
IL-21 Optimizes the CAR-T Cell Preparation Through Improving Lentivirus Mediated Transfection Efficiency of T Cells and Enhancing CAR-T Cell Cytotoxic Activities
Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
A Rapid and Efficient Screening System for Neutralizing Antibodies and Its Application for SARS-CoV-2
p38 inhibition enhances TCR-T cell function and antagonizes the immunosuppressive activity of TGF-β
TRAIL-R1-Targeted CAR-T Cells Exhibit Dual Antitumor Efficacy
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
TRAIL-R1-targeted chimeric antigen receptor T cells exhibit dual antitumor effects
Long Noncoding RNAs Control the Modulation of Immune Checkpoint Molecules in Cancer
Identification of long-term survival-associated gene in breast cancer
A rapid and efficient screening system for neutralizing antibodies and its application for the discovery of potent neutralizing antibodies to SARS-CoV-2 S-RBD
Identification of Cross-Reactive CD8 <sup>+</sup> T Cell Receptors with High Functional Avidity to a SARS-CoV-2 Immunodominant Epitope and Its Natural Mutant Variants
A key linear epitope for a potent neutralizing antibody to SARS-CoV-2 S-RBD
Immune characteristics analysis reveals two key inflammatory factors correlated to the expressions of SARS-CoV-2 S1-specific antibodies
A rapid and efficient screening system for neutralizing antibodies and its application for SARS-CoV-2
Long Noncoding RNA Linc00152 Functions as a Tumor Propellant in Pan-Cancer
Identification of Novel Epitopes with Agonistic Activity for the Development of Tumor Immunotherapy Targeting TRAIL-R1
Fully human monoclonal antibodies to TRAIL-R1 enhance TRAIL-induced apoptosis via activation of caspase-8 pathway