Area of research
Molecular Biology · Genetics
Research interest
Research interests include Glioma Diagnosis and Treatment, Epigenetics and DNA Methylation, Cancer, Hypoxia, and Metabolism, and Birth, Development, and Health.
Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
A new IDH-independent hypermethylation phenotype is associated with astrocyte-like cell state in glioblastoma
Overcoming tyrosine kinase inhibitor resistance in lung cancer brain metastasis with CTLA4 blockade
A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs
SOX10 mediates glioblastoma cell-state plasticity
Distinct aneuploid evolution of astrocytoma and glioblastoma during recurrence
A multidimensional atlas of human glioblastoma organoids reveals highly coordinated molecular networks and effective drugs
Integrative Ranking of Enhancer Networks Facilitates the Discovery of Epigenetic Markers in Cancer
Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype
Hypoxia and the hypoxia inducible factor 1α activate protein kinase A by repressing RII beta subunit transcription
Integrative Ranking Of Enhancer Networks Facilitates The Discovery Of Epigenetic Markers In Cancer
Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis
GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile
Branched‐chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype
The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer
confFuse: High-Confidence Fusion Gene Detection across Tumor Entities
confFuse: high-confidence fusion gene detection across tumor entities
RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors
RSUME regulates tumorigenesis and metastasis in pancreatic neuroendocrine tumors