Area of research
Genetics · Cancer Research
Research interest
Research interests include Glioma Diagnosis and Treatment, Cancer Genomics and Diagnostics, Epigenetics and DNA Methylation, and Genomic variations and chromosomal abnormalities.
Subtyping Burkitt Lymphoma by <scp>DNA</scp> Methylation
A new IDH-independent hypermethylation phenotype is associated with astrocyte-like cell state in glioblastoma
Subgrouping germinal center-derived B-cell lymphomas based on machine learning-deduced DNA methylation modules
SOX10 mediates glioblastoma cell-state plasticity
Methylation-directed regulatory networks determine enhancing and silencing of mutation disease driver genes and explain inter-patient expression variation
Branched-chain amino acid transaminase 1 regulates glioblastoma cell plasticity and contributes to immunosuppression
BCAT1 regulates glioblastoma cell plasticity and contributes to immunosuppression
The genomic and transcriptional landscape of primary central nervous system lymphoma
Rapid, adaptable and sensitive Cas13-based COVID-19 diagnostics using ADESSO
BCAT1 redox function maintains mitotic fidelity
Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas
Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas
A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors
ADESSO: a rapid, adaptable and sensitive Cas13-based COVID-19 diagnostic platform
Methylation-mediated retuning on the enhancer-to-silencer activity scale of networked regulatory elements guides driver-gene misregulation
Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype
Leucine and branched-chain amino acid metabolism contribute to the growth of bone sarcomas by regulating AMPK and mTORC1 signaling
Pilocytic astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response
A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies
Longitudinal molecular trajectories of diffuse glioma in adults
Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis
Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma
GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile
Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
Branched‐chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype
The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer
PII Protein-Derived FRET Sensors for Quantification and Live-Cell Imaging of 2-Oxoglutarate
COMPREHENSIVE EPIGENETIC AND TRANSCRIPTIONAL SURVEY OF THE “IMPRINTOME” IN NORMAL <scp>B</scp>‐CELLS AND GERMINAL CENTER DERIVED <scp>B</scp>‐CELL LYMPHOMAS OF THE <scp>MMML</scp> AND <scp>ICGC MMML‐S</scp>EQ NETWORKS
Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes