Area of research
Genetics · Pulmonary and Respiratory Medicine
Research interest
Research interests include Glioma Diagnosis and Treatment, Brain Metastases and Treatment, Chromatin Remodeling and Cancer, and Neuroblastoma Research and Treatments.
The effect of TERT promoter mutation on predicting meningioma outcomes: a multi-institutional cohort analysis
Mixed histiocytic neoplasms: A multicentre series revealing diverse somatic mutations and responses to targeted therapy
Vorasidenib and ivosidenib in IDH1-mutant low-grade glioma: a randomized, perioperative phase 1 trial
Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors—A prospective study and guidelines for clinical testing
Upfront molecular targeted therapy for the treatment of BRAF-mutant pediatric high-grade glioma
Multi-institutional study of the frequency, genomic landscape, and outcome of IDH-mutant glioma in pediatrics
Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study
Debio1347, an Oral FGFR Inhibitor: Results From a Single-Center Study in Pediatric Patients With Recurrent or Refractory FGFR-Altered Gliomas
Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes
Cerebrospinal fluid circulating tumor cells as a quantifiable measurement of leptomeningeal metastases in patients with HER2 positive cancer
Randomized phase II study of rituximab, methotrexate (MTX), procarbazine, vincristine, and cytarabine (R-MPV-A) with and without low-dose whole-brain radiotherapy (LD-WBRT) for newly diagnosed primary CNS lymphoma (PCNSL).
Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions
Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY)
Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study
Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization
Marked Response of a Hypermutated ACTH-Secreting Pituitary Carcinoma to Ipilimumab and Nivolumab
Acquired <i>ALK</i> and <i>RET</i> Gene Fusions as Mechanisms of Resistance to Osimertinib in <i>EGFR</i> -Mutant Lung Cancers
Multinodular and vacuolating neuronal tumor of the cerebrum is a clonal neoplasm defined by genetic alterations that activate the MAP kinase signaling pathway
Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma
A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle
A Secondary Mutation in <i>BRAF</i> Confers Resistance to RAF Inhibition in a <i>BRAF</i> V600E-Mutant Brain Tumor
EMBR-02. RECURRENT HOMOZYGOUS DELETION OF DROSHA AND MICRODUPLICATION OF PDE4DIP CONTAINING THE ANCESTRAL DUF1220 DOMAIN IN PINEOBLASTOMA
Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma
A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway
Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study