Area of research
Molecular Biology
Research interest
Research interests include CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, Advanced biosensing and bioanalysis techniques, and RNA Interference and Gene Delivery.
Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease
Base editing of trinucleotide repeats that cause Huntington’s disease and Friedreich’s ataxia reduces somatic repeat expansions in patient cells and in mice
Branched chemically modified poly(A) tails enhance the translation capacity of mRNA
High-throughput evaluation of genetic variants with prime editing sensor libraries
Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity
Generating experimentally unrelated target molecule-binding highly functionalized nucleic-acid polymers using machine learning
Engineered pegRNAs improve prime editing efficiency
Author Correction: Engineered pegRNAs improve prime editing efficiency
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