Area of research
Physiology · Neurology
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Parkinson's Disease Mechanisms and Treatments, and Traumatic Brain Injury Research.
Brain Sphingolipid and Phospholipid Levels Are Altered in <scp>XK</scp> Disease
Aldehyde-based cryopreservation of whole brains
TDP-43 loss induces cryptic polyadenylation in ALS/FTD
Lymphoid gene expression supports neuroprotective microglia function
Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration
Primary age-related tauopathy
Cognitive and neuropsychological trajectories in patients with mixed neurodegenerative pathologies
A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes
Evaluating ultrastructural preservation quality in banked brain tissue
White matter microstructure is differentially impacted by cerebral amyloid angiopathy, neurofibrillary tangles, and neuritic plaque co‐pathology
Chronic traumatic encephalopathy neuropathologic change in the Late Effects of Traumatic Brain Injury project: Findings in a community autopsy cohort
Mechanical perfusion in brain banking: methods of assessment and relationship to the postmortem interval
Genetic variation in TMEM106B alters microglial activation and cytokine responses in chronic traumatic encephalopathy
Copy Number Variation and Haplotype Analysis of <scp>17q21.31</scp> Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells
Amygdala-predominant Lewy bodies associate with cognitive decline and amygdala atrophy in Alzheimer’s disease neuropathological change
Structural Compression and Entorhinal Vulnerability: Linking Tentorial Adjacency to Tau Burden and Dementia Progression
Evaluating ultrastructural preservation quality in banked brain tissue
Towards an AI biomedical scientist: Accelerating discoveries in neurodegenerative disease
Longitudinal assessment of cognitive decline and resilience in high-level Alzheimer disease neuropathologic change
Modulation of Amyloid‐beta Metabolism by TIMP2 and MMP2 Through Extracellular Matrix Interactions in Mouse Models of Alzheimer's Pathology
Classifying AD and PART: An Epigenetic Signature of Cognitive Resilience
From novel targets to potential therapies: development of antisense oligonucleotides for progressive supranuclear palsy
A novel hierarchical framework elucidating regional differences in α-synuclein and tau co-pathology in military veterans with parkinsonism
Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson’s disease
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model
Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease
Cognitive, functional, and neuropsychiatric correlates of regional tau pathology in autopsy-confirmed chronic traumatic encephalopathy
Disentangling and quantifying the relative cognitive impact of concurrent mixed neurodegenerative pathologies
Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy
Biomarker‐Based Approach to α‐Synucleinopathies: Lessons from Neuropathology