Area of research
Neurology · Cellular and Molecular Neuroscience
Research interest
Research interests include Neurological disorders and treatments, Parkinson's Disease Mechanisms and Treatments, Genetic Neurodegenerative Diseases, and Botulinum Toxin and Related Neurological Disorders.
The Spectrum of Neurologic Phenotypes Associated With <scp><i>NUS1</i></scp> Pathogenic Variants: A Comprehensive Case Series
Alpha-synuclein in Parkinson's disease: Embracing debate, exercising skepticism
Integrated Stress Response Signatures Drive Monocyte Dysfunction in <i>GBA1</i> - and <i>LRRK2</i> -Linked Parkinson’s Disease
The α-synuclein seed amplification assay: Interpreting a test of Parkinson's pathology
Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy
<i>LRRK2</i> G2019S variant is associated with transcriptional changes in Parkinson’s disease human myeloid cells under proinflammatory environment
Generating a novel and reliable human iPSC‐derived midbrain organoid model of sporadic progressive supranuclear palsy
Assessing Internal Reproducibility Within a Parkinson’s Disease Cohort by Leveraging an Independent Larger Dataset
Neuropathologic and transcriptomic analysis reveals abnormal stress response in sporadic progressive supranuclear palsy autopsy brain tissue and human iPSC‐derived midbrain organoids
Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy
Investigating mechanisms of sporadic progressive supranuclear palsy in autopsy‐validated human iPSC‐derived midbrain organoids and human brain tissue
17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes
Transcriptome deregulation of peripheral monocytes and whole blood in GBA-related Parkinson’s disease
Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells
Transcriptome deregulation of peripheral monocytes in <i>GBA</i> -related Parkinson’s disease
Alcohol-Responsive Hyperkinetic Movement Disorders—a Mechanistic Hypothesis
Discordant transcriptional signatures of mitochondrial genes in Parkinson’s disease human myeloid cells
Essential tremor-plus: a controversial new concept
Functional and structural neural bases of task specificity in isolated focal dystonia
Early‐onset pathologically proven multiple system atrophy with LRRK2 G2019S mutation
Mirabegron in patients with Parkinson disease and overactive bladder symptoms: A retrospective cohort
Outcomes of intradetrusor onabotulinum toxin A injection in patients with Parkinson's disease
Research Priorities in Limb and Task-Specific Dystonias
The diagnostic value of saccades in movement disorder patients: a practical guide and review
Cognitive and Motor Function in Long-Duration<i>PARKIN</i>-Associated Parkinson Disease
Exome Sequencing Reveals De Novo WDR45 Mutations Causing a Phenotypically Distinct, X-Linked Dominant Form of NBIA
Mutations in the Gene PRRT2 Cause Paroxysmal Kinesigenic Dyskinesia with Infantile Convulsions