Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZA
Area of research
Epidemiology · Molecular Biology
Research interest
Research interests include Influenza Virus Research Studies, Genomics and Phylogenetic Studies, Genomic variations and chromosomal abnormalities, and Chromosomal and Genetic Variations.
Near real-time data on the human neutralizing antibody landscape to influenza virus as of early 2026 to inform vaccine-strain selection
Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025
High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains
High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains
Timely vaccine strain selection and genomic surveillance improves evolutionary forecast accuracy of seasonal influenza A/H3N2
Timely vaccine strain selection and genomic surveillance improve evolutionary forecast accuracy of seasonal influenza A/H3N2
High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains
Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin
High-throughput sequencing-based neutralization assay reveals how repeated vaccinations impact titers to recent human H1N1 influenza strains
Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States
Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States
Dimensionality reduction distills complex evolutionary relationships in seasonal influenza and SARS-CoV-2
Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States
Joint visualization of seasonal influenza serology and phylogeny to inform vaccine composition
Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2
Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition
Cryptic transmission of SARS-CoV-2 in Washington state
A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo
An evolutionary driver of interspersed segmental duplications in primates
dms-view: Interactive visualization tool for deep mutational scanning data
An evolutionary driver of interspersed segmental duplications in primates
Nextstrain: real-time tracking of pathogen evolution
Recurrent structural variation, clustered sites of selection, and disease risk for the complement factor H ( <i>CFH</i> ) gene family
The evolution and population diversity of human-specific segmental duplications
The birth of a human-specific neural gene by incomplete duplication and gene fusion
Complex Relationships between Chromatin Accessibility, Sequence Divergence, and Gene Expression in Arabidopsis thaliana
Epigenetic origin of evolutionary novel centromeres
A 3-way hybrid approach to generate a new high-quality chimpanzee reference genome (Pan_tro_3.0)
Long-read sequence assembly of the gorilla genome
Long-read sequencing and de novo assembly of a Chinese genome