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Mehdi Touat

Université Paris 1 Panthéon-Sorbonne · FR
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Area of research
Genetics · Cancer Research
Research interest
Research interests include Glioma Diagnosis and Treatment, Brain Metastases and Treatment, Cancer Genomics and Diagnostics, and Radiomics and Machine Learning in Medical Imaging.
h-index
36
citations
7,005
works
275
NIH funding
primary concept
Medicine
email

Recent publications

Glioblastoma in adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
Neuro-Oncology 2025cited by 26position: middledoi
Vorasidenib in IDH1-mutant or IDH2-mutant low-grade glioma (INDIGO): secondary and exploratory endpoints from a randomised, double-blind, placebo-controlled, phase 3 trial
The Lancet Oncology 2025cited by 11position: middledoi
A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas
Nature Communications 2025cited by 6position: middledoi
A Specific Methylation Class Identifies BAP1‐Deficient Meningiomas, Including Meningeal Tumours With Poorly Differentiated Nonrhabdoid Histology
Neuropathology and Applied Neurobiology 2025cited by 3position: middledoi
P12.59.B CONDITIONAL SURVIVAL ANALYSIS IN IDH-MUTANT HIGH-GRADE GLIOMAS: AN USEFUL TOOL IN CLINICAL PRACTICE
Neuro-Oncology 2025cited by 0position: middledoi
TMOD-12. Preclinical and clinical assessment of chemoradiation after mutant IDH inhibitor treatment in IDH-mutant glioma
Neuro-Oncology 2025cited by 0position: middledoi
BIOS-01. CONDITIONAL SURVIVAL ANALYSIS IN IDH-MUTANT HIGH-GRADE GLIOMAS: AN USEFUL TOOL IN CLINICAL PRACTICE
Neuro-Oncology 2025cited by 0position: middledoi
The biological significance of tumor grade, age, enhancement, and extent of resection in IDH-mutant gliomas: How should they inform treatment decisions in the era of IDH inhibitors?
Neuro-Oncology 2024cited by 66position: middledoi
Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma
Cancer Cell 2024cited by 51position: middledoi
Survival Outcomes Associated With First-Line Procarbazine, CCNU, and Vincristine or Temozolomide in Combination With Radiotherapy in IDH-Mutant 1p/19q-Codeleted Grade 3 Oligodendroglioma
Journal of Clinical Oncology 2024cited by 27position: middledoi
Contemporary prognostic signatures and refined risk stratification of gliomas: An analysis of 4400 tumors
Neuro-Oncology 2024cited by 26position: middledoi
Central nervous system tumors in adolescents and young adults: A Society for Neuro-Oncology Consensus Review on diagnosis, management, and future directions
Neuro-Oncology 2024cited by 23position: middledoi
Updated EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection—Update 1
Neuro-Oncology 2024cited by 20position: middledoi
The role of vorasidenib in the treatment of isocitrate dehydrogenase-mutant glioma
Neuro-Oncology 2024cited by 16position: middledoi
A comparative analysis of IDH-mutant glioma in pediatric, young adult, and older adult patients
Neuro-Oncology 2024cited by 13position: middledoi
CTNI-53. A GLOBAL, RANDOMIZED, DOUBLE-BLINDED, PHASE 3 STUDY OF VORASIDENIB VERSUS PLACEBO IN PATIENTS WITH ADULT-TYPE DIFFUSE GLIOMA WITH AN IDH1/2 MUTATION (INDIGO): UPDATED EFFICACY RESULTS
Neuro-Oncology 2024cited by 7position: middledoi
A Randomized, Double-blind, Phase 3 Study of Vorasidenib Versus Placebo in Patients with Mutant IDH1/2 Diffuse Glioma (INDIGO): Analysis of Health-related Quality of Life, Neurocognition and Seizures (PL5.003)
Neurology 2024cited by 6position: middledoi
A diverse landscape of FGFR alterations and co-mutations defines novel therapeutic strategies in pediatric low-grade gliomas
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 4position: middledoi
10311- ACT-19 A GLOBAL, RANDOMIZED, DOUBLE-BLINDED, PHASE 3 STUDY OF VORASIDENIB VERSUS PLACEBO IN PATIENTS WITH ADULT-TYPE DIFFUSE GLIOMA WITH AN IDH1/2 MUTATION (INDIGO): UPDATED EFFICACY RESULTS
Neuro-Oncology Advances 2024cited by 3position: middledoi
OS12.7.A INTEGRATED DIGITAL PATHOLOGY AND TRANSCRIPTOMIC ANALYSIS OF ADULT GLIOMAS WITH HIGH LYMPHOCYTE INFILTRATION IDENTIFIES CELLULAR AND SPATIAL DETERMINANTS OF IMMUNE INFILTRATION WITH PROGNOSTIC VALUE
Neuro-Oncology 2024cited by 2position: middledoi
KS04.6.A GLIOMAS WITH PLEOMORPHIC AND PSEUDOPAPILLARY FEATURES (GPAP) ARE CIRCUMSCRIBED TUMORS WITH LONG-TERM SURVIVAL
Neuro-Oncology 2024cited by 1position: middledoi
Spectrum of IDH-mutant tumors in Ollier-Maffucci disease: the triple interaction theory
Orphanet Journal of Rare Diseases 2024cited by 1position: lastdoi
KS02.5.A THE ONCOMETABOLITE D-2-HYDROXYGLUTARATE PROMOTES DNA HYPERMETHYLATION AT LINEAGE-SPECIFIC ENHANCERS CONTROLLING MICROGLIAL ACTIVATION IN IDH-MUTATED GLIOMAS
Neuro-Oncology 2024cited by 0position: middledoi
Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma
New England Journal of Medicine 2023cited by 690position: middledoi
EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection
Neuro-Oncology 2023cited by 99position: middledoi
A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation
Acta Neuropathologica 2023cited by 69position: middledoi
Inaugural Results of the Individualized Screening Trial of Innovative Glioblastoma Therapy: A Phase II Platform Trial for Newly Diagnosed Glioblastoma Using Bayesian Adaptive Randomization
Journal of Clinical Oncology 2023cited by 46position: middledoi
QOL-26. A RANDOMIZED, DOUBLE-BLIND PHASE 3 STUDY OF VORASIDENIB VS PLACEBO IN PATIENTS WITH MUTANT <i>IDH1/2</i>DIFFUSE GLIOMA (INDIGO): ANALYSIS OF HEALTH-RELATED QUALITY OF LIFE, NEUROCOGNITION AND SEIZURES
Neuro-Oncology 2023cited by 19position: middledoi
LTBK-06. IMPACT OF VORASIDENIB TREATMENT ON MUTANT <i>IDH1</i> OR <i>IDH2</i> DIFFUSE GLIOMA TUMOR GROWTH RATE: RESULTS FROM THE RANDOMIZED, DOUBLE-BLIND, PHASE 3 INDIGO STUDY
Neuro-Oncology 2023cited by 18position: middledoi
498O INDIGO: A randomized, double-blinded, phase III study of vorasidenib versus placebo in IDH1 or IDH2 low-grade glioma
Annals of Oncology 2023cited by 2position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Patrick Y. Wen · Harvard University14 papers (2016–2024)Ahmed Idbaïh · Institut de Myologie10 papers (2018–2024)Marc Sanson · Allen Institute for Brain Science9 papers (2014–2025)Franck Bielle · Centre National de la Recherche Scientifique8 papers (2018–2025)Wolfgang Wick · Heidelberger Institut für Radioonkologie7 papers (2020–2024)Ingo K. Mellinghoff · University of Colorado Denver7 papers (2016–2024)Martin J. van den Bent · St James's University Hospital6 papers (2020–2024)Benjamin M. Ellingson · Sylvester Comprehensive Cancer Center6 papers (2016–2024)Timothy F. Cloughesy · UCLA Medical Center6 papers (2016–2024)Ghazaleh Tabatabai · Goethe University Frankfurt5 papers (2022–2023)David A. Reardon · Massachusetts Institute of Technology5 papers (2021–2023)Katherine B. Peters · Duke University4 papers (2020–2024)Karima Mokhtari · NeurON : Interface Neuro-machine4 papers (2018–2021)Ana Maia · The Netherlands Cancer Institute4 papers (2022–2023)Shuchi S. Pandya · National Medical Research Center of Dentistry and Maxillofacial Surgery4 papers (2020–2024)Jean‐Yves Delattre · Centre National de la Recherche Scientifique4 papers (2018–2021)Mirjam Renovanz · University Children's Hospital Tübingen4 papers (2022–2023)María Vieito · Instituto de Investigación Sanitaria de Santiago4 papers (2022–2023)Lori Steelman · Servier (France)4 papers (2017–2024)Khê Hoang‐Xuan · County Hospital4 papers (2018–2021)
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