Area of research
Molecular Biology
Research interest
Research interests include Genomics and Chromatin Dynamics, RNA and protein synthesis mechanisms, Epigenetics and DNA Methylation, and Gene expression and cancer classification.
RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation
Novel <i>SOX10</i> indel mutations drive schwannomas through impaired transactivation of myelination gene programs
Ferroptosis-Related Gene Signature Predicts the Prognosis of Skin Cutaneous Melanoma and Response to Immunotherapy
Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells
Measuring DNA mechanics on the genome scale
Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation
Single-Cell Transcriptomics Reveals Spatial and Temporal Turnover of Keratinocyte Differentiation Regulators
Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution
Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
High accuracy label-free classification of single-cell kinetic states from holographic cytometry of human melanoma cells
Inhibition of mTOR induces a paused pluripotent state
YAP Induces Human Naive Pluripotency
Intratumoral Heterogeneity of the Epigenome
The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer
DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors
The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma
The Genetics of Splicing in Neuroblastoma
Systematic Identification of Barriers to Human iPSC Generation
Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast
HiTSelect: a comprehensive tool for high-complexity-pooled screen analysis
Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma
Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
Integration of Genome-wide Approaches Identifies lncRNAs of Adult Neural Stem Cells and Their Progeny In Vivo
<i>BCL2A1</i> is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition
Bivalent Chromatin Marks Developmental Regulatory Genes in the Mouse Embryonic Germline In Vivo
Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytes
Normalization, bias correction, and peak calling for ChIP-seq
Sox1 marks an activated neural stem/progenitor cell in the hippocampus
Polycomb-Like 3 Promotes Polycomb Repressive Complex 2 Binding to CpG Islands and Embryonic Stem Cell Self-Renewal
CHANCE: comprehensive software for quality control and validation of ChIP-seq data
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