Area of research
Hematology · Molecular Biology
Research interest
Research interests include Biology, Transcription factor, RUNX1, Cancer research, Myeloid leukemia, and Epigenetics.
Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells
Transcriptional reprogramming by mutated IRF4 in lymphoma
Epigenetic regulator genes direct lineage switching in <i>MLL/AF4</i> leukemia
A new type of transcriptional reprogramming by an IRF4 mutation in lymphoma
RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction
The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation
Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia
Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers
UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO
NFATc1 releases BCL6‐dependent repression of CCR2 agonist expression in peritoneal macrophages from<i>Saccharomyces cerevisiae</i>infected mice
Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: Its more than NF-κB!
Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma
Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia
Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis