Area of research
Immunology · Genetics
Research interest
Research interests include Immunodeficiency and Autoimmune Disorders, Blood disorders and treatments, Immune Cell Function and Interaction, and T-cell and B-cell Immunology.
The intestinal microbiome and metabolome discern disease severity in cytotoxic T-lymphocyte-associated protein 4 deficiency
AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling
Re-evaluation of the contribution of <i>TNFRSF13B</i> variants to antibody deficiency
Lipocalin-2 expression identifies an intestinal regulatory neutrophil population during acute graft-versus-host disease
Diagnostic evaluation of paediatric autoimmune lymphoproliferative immunodeficiencies (ALPID): a prospective cohort study
ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA
Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection
Evaluation and Management of Deficiency of Adenosine Deaminase 2
JAKs and STATs from a Clinical Perspective: Loss-of-Function Mutations, Gain-of-Function Mutations, and Their Multidimensional Consequences
Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia
Precision medicine in monogenic inflammatory bowel disease: proposed mIBD REPORT standards
Telomere biology disorders may manifest as common variable immunodeficiency (CVID)
The GAIN Registry — a New Prospective Study for Patients with Multi-organ Autoimmunity and Autoinflammation
Future Directions in the Diagnosis and Treatment of APDS and IEI: a Survey of German IEI Centers
Studying severe long COVID to understand post-infectious disorders beyond COVID-19
Autoantibodies against type I IFNs in patients with critical influenza pneumonia
Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency
Genomic characterization of lymphomas in patients with inborn errors of immunity
Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency–Associated Villous Atrophy and Norovirus Infection
Dysregulated PI3K Signaling in B Cells of CVID Patients
The expansion of human T-bet <sup>high</sup> CD21 <sup>low</sup> B cells is T cell dependent
Therapeutic options for CTLA-4 insufficiency
Biochemically deleterious human <i>NFKB1</i> variants underlie an autosomal dominant form of common variable immunodeficiency
Establishing the Molecular Diagnoses in a Cohort of 291 Patients With Predominantly Antibody Deficiency by Targeted Next-Generation Sequencing: Experience From a Monocentric Study
Genetic Analysis of a Cohort of 275 Patients with Hyper-IgE Syndromes and/or Chronic Mucocutaneous Candidiasis
Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction
What can clinical immunology learn from inborn errors of epigenetic regulators?
Therapeutic targeting of endoplasmic reticulum stress in acute graft-<i>versus</i>-host disease