Area of research
Immunology · Oncology
Research interest
Research interests include Immune Cell Function and Interaction, Immunodeficiency and Autoimmune Disorders, T-cell and B-cell Immunology, and Immunotherapy and Immune Responses.
Neuro-epithelial circuits promote sensory convergence and intestinal immunity
Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted
The XCL1–XCR1 axis supports intestinal tissue residency and antitumor immunity
Diagnostic evaluation of paediatric autoimmune lymphoproliferative immunodeficiencies (ALPID): a prospective cohort study
The β1-adrenergic receptor links sympathetic nerves to T cell exhaustion
Metabolic programs of T cell tissue residency empower tumour immunity
JAKs and STATs from a Clinical Perspective: Loss-of-Function Mutations, Gain-of-Function Mutations, and Their Multidimensional Consequences
Activated phosphoinositide 3-kinase δ syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity
Insights into phenotypic and functional <scp>CD8</scp><sup>+</sup> T<sub>RM</sub> heterogeneity
Transcriptional programming of CD4 <sup>+</sup> T <sub>RM</sub> differentiation in viral infection balances effector- and memory-associated gene expression
Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments
Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome
High-dimensional profiling reveals Tc17 cell enrichment in active Crohn’s disease and identifies a potentially targetable signature
Exhaustion of CD39-Expressing CD8+ T Cells in Crohn’s Disease Is Linked to Clinical Outcome
Evaluation of Laboratory and Sonographic Parameters for Detection of Portal Hypertension in Patients with Common Variable Immunodeficiency
Early-onset autoimmunity associated with SOCS1 haploinsufficiency
Neuroinflammatory Disease as an Isolated Manifestation of Hemophagocytic Lymphohistiocytosis
A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS
Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2
The German National Registry of Primary Immunodeficiencies (2012–2017)
Distinct molecular response patterns of activating STAT3 mutations associate with penetrance of lymphoproliferation and autoimmunity
Disease Evolution and Response to Rapamycin in Activated Phosphoinositide 3-Kinase δ Syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry
Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation